1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride

Base Information

• Chemical Name: 1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride
• CAS No.: 79886-12-7
• Molecular Formula: C₁₀H₁₆N₂*2ClH
• Molecular Weight: 237.172
• Mol file: 79886-12-7.mol

Synonyms:1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride

Chemical Property of 1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride

There total 2 articles about 1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-nitrobenzyl)-2-nitropropane (5440-67-5) → 1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride (79886-12-7)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; Yield given. Multistep reaction; 1.) ethanol, 8 h, reflux;

Reference yield:

4-nitrobenzyl chloride (100-14-1) → 1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride (79886-12-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / Na, EtOH / 12 h / Heating

2: 1.) H₂, 2.) HCl / 1.) 10percent Pd/C / 1.) ethanol, 8 h, reflux

With hydrogenchloride; ethanol; hydrogen; sodium; palladium on activated charcoal;

Reference yield: 82.0%

1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride (79886-12-7) → 1,1-dimethyl-2-(4-methoxyphenyl)ethylamine hydrochloride (56490-93-8)

Guidance literature:

With hydrogenchloride; sodium nitrite; In methanol; water; 1.) 5 deg C - room temp., 2.) 3 h, reflux;

upstream raw materials:

2-(4-nitrobenzyl)-2-nitropropane

4-nitrobenzyl chloride

Downstream raw materials:

1,1-dimethyl-2-(4-methoxyphenyl)ethylamine hydrochloride

Phentermin