56490-93-8Relevant articles and documents
IMPROVED PROCESS FOR THE MANUFACTURE OF R-6-HYDROXY-8-[1-HYDROXY-2-[2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYLAMINOETHYL]-2H-1,4-BENZOXAZIN-3(4H)-ONE HYDROCHLORIDE
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, (2018/07/29)
The present invention provides an improved process for the manufacture (R)-6- hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethyl-ethylamino-ethyl]-2H-1,4- benzoxazin-3(4H)-one, in high purity and high yield, through the use of 1,1-dimethyl-2- (4-met
1-DIPHENYLPHOSPHINYL-2,2-DIMETHYLAZIRIDINE - A NEW PRECURSOR OF α,α-DIMETHYLARYLALKYLAMINES
Buchowiecki, Wieslaw,Grosman-Zjawiona, Zofia,Zjawiony, Jordan
, p. 1245 - 1248 (2007/10/02)
The new synthesis of α,α-dimethylarylalkylamines from 1-diphenylphosphinyl-2,2-dimethylaziridine is described.
Novel benzylalcohol derivative and process for preparing the same
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, (2008/06/13)
A benzylalcohol derivative of the formula: STR1 wherein R is hydroxy, benzyloxy, alkoxy of one to 4 carbon atoms or halogen, and Ring A is monomethoxyphenyl, dimethoxyphenyl, trimethoxyphenyl or 3,4-methylenedioxyphenyl is prepared by reducing a compound of the formula: STR2 wherein R' is benzyloxy, alkoxy of one to 4 carbon atoms or halogen, and Ring A is the same as defined above, and when R' is benzyloxy, if required, further subjecting the product to catalytic hydrogenation. The compounds (I) and pharmaceutically acceptable acid addition salts thereof are used as anti-diabetic agents.