56490-93-8

Usage

Uses

Used in Pharmaceutical Industry:
Phenethylamine, alpha,alpha-dimethyl-p-methoxy-, hydrochloride is used as an active pharmaceutical ingredient for the development of prescription medications. Its stimulant effects on the central nervous system make it a potential candidate for the treatment of certain psychiatric disorders.
Used in Research Applications:
In the field of scientific research, Phenethylamine, alpha,alpha-dimethyl-p-methoxy-, hydrochloride is used as a research chemical to study its effects on the central nervous system. This helps researchers understand its potential therapeutic applications and develop new treatments for psychiatric disorders.

InChI:InChI=1/C11H17NO.ClH/c1-11(2,12)8-9-4-6-10(13-3)7-5-9;/h4-7H,8,12H2,1-3H3;1H

Upstream product

• 5440-67-5 2-(4-nitrobenzyl)-2-nitropropane 
• 110-71-4 1,2-dimethoxyethane 
• 76072-36-1 1-(4-methoxyphenyl)-1-chloro-2-methyl-2-nitropropane 
• 56490-94-9 1-(2-amino-2-methylpropyl)-4-methoxybenzene 
• 824-94-2 p-methoxybenzyl chloride 
• 29206-06-2 2,2-dimethyl-3-(4-methoxyphenyl)propionic acid 
• 1035155-37-3 ethyl 2,2-dimethyl-3-(4-methoxyphenyl)propanoate 
• 85628-47-3 4-Methoxy-(2-methyl-2-nitropropyl)benzol 
• 16066-97-0 1-nitro-1,1-dimethyl-2-(4-hydroxyphenyl]ethane 
• 100-14-1 4-nitrobenzyl chloride 
• 97847-81-9 C₂₃H₂₆NO₂P 
• 79886-12-7 1-(p-aminophenyl)-2-methyl-2-propylamine dihydrochloride 

Downstream Products

• 926319-48-4 6-(phenylmethoxy)-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride 

Relevant academic research and scientific papers

IMPROVED PROCESS FOR THE MANUFACTURE OF R-6-HYDROXY-8-[1-HYDROXY-2-[2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYLAMINOETHYL]-2H-1,4-BENZOXAZIN-3(4H)-ONE HYDROCHLORIDE

The present invention provides an improved process for the manufacture (R)-6- hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethyl-ethylamino-ethyl]-2H-1,4- benzoxazin-3(4H)-one, in high purity and high yield, through the use of 1,1-dimethyl-2- (4-met

CALCILYTIC COMPOUNDS

Novel calcilytic compounds, pharmaceutical compositions, methods of synthesis and methods of using them are provided.

Derivatives related to betaxolol with α- and β-adrenergic activities

The paper describes the synthesis and the pharmacological evaluation of some derivatives of betaxolol, all with an N-aralkylamine instead of the tertiobutylamine. These compounds have been tested for β1-adrenergic receptor antagonism on guinea pig atria, β2-adrenergic receptor antagonism on guinea pig trachea and α-adrenergic blocking activity on rat aorta. Compound U12 with a marked α-blocking activity and compound R8 with a β1/α ratio = 1 were selected for a haemodynamic study in the dog. The decrease in cardiac work and the diminution of total peripheral resistance exhibited by U12 are consistent with a dual α/β-blocking agent. Finally, structure-activity relationships are discussed.

1-DIPHENYLPHOSPHINYL-2,2-DIMETHYLAZIRIDINE - A NEW PRECURSOR OF α,α-DIMETHYLARYLALKYLAMINES

The new synthesis of α,α-dimethylarylalkylamines from 1-diphenylphosphinyl-2,2-dimethylaziridine is described.

Novel benzylalcohol derivative and process for preparing the same

A benzylalcohol derivative of the formula: STR1 wherein R is hydroxy, benzyloxy, alkoxy of one to 4 carbon atoms or halogen, and Ring A is monomethoxyphenyl, dimethoxyphenyl, trimethoxyphenyl or 3,4-methylenedioxyphenyl is prepared by reducing a compound of the formula: STR2 wherein R' is benzyloxy, alkoxy of one to 4 carbon atoms or halogen, and Ring A is the same as defined above, and when R' is benzyloxy, if required, further subjecting the product to catalytic hydrogenation. The compounds (I) and pharmaceutically acceptable acid addition salts thereof are used as anti-diabetic agents.