Lys(N-Cbz)-Phe-OMe

Base Information

• Chemical Name: Lys(N-Cbz)-Phe-OMe
• CAS No.: 58328-63-5
• Molecular Formula: C₂₄H₃₁N₃O₅
• Molecular Weight: 441.527
• Mol file: 58328-63-5.mol

Synonyms:Lys(N-Cbz)-Phe-OMe

Chemical Property of Lys(N-Cbz)-Phe-OMe

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Lys(N-Cbz)-Phe-OMe

There total 6 articles about Lys(N-Cbz)-Phe-OMe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Boc-Lys(Z)-Phe-OMe (18671-00-6) → Lys(N-Cbz)-Phe-OMe (58328-63-5)

Guidance literature:

With hydrogenchloride; acetic acid;

Reference yield:

Boc-Lys(Z)-OSu (34404-36-9) → Lys(N-Cbz)-Phe-OMe (58328-63-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / Et₃N / CH₂Cl₂ / 20 °C

2: aq. HCl / dioxane; CH₂Cl₂ / 2 h

With hydrogenchloride; triethylamine; In 1,4-dioxane; dichloromethane;

DOI:10.1021/ol048845t

Reference yield:

methyl (2S)-2-amino-3-phenylpropanoate (2577-90-4) → Lys(N-Cbz)-Phe-OMe (58328-63-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / Et₃N / CH₂Cl₂ / 20 °C

2: aq. HCl / dioxane; CH₂Cl₂ / 2 h

With hydrogenchloride; triethylamine; In 1,4-dioxane; dichloromethane;

DOI:10.1021/ol048845t

upstream raw materials:

Boc-Lys(Z)-Phe-OMe

2,2-dimethoxy-propane

Boc-Lys(Z)-OSu

methyl (2S)-2-amino-3-phenylpropanoate

Downstream raw materials:

C₂₇H₃₃N₃O₆

C₄₄H₄₅N₃O₆

Boc-V-(δ-Boc)K-F

2-[6-tert-butoxycarbonylamino-2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-hexanoylamino]-3-phenyl-propionic acid methyl ester