2-(2-Bromoethoxy)-1,4-dichlorobenzene

Base Information

• Chemical Name: 2-(2-Bromoethoxy)-1,4-dichlorobenzene
• CAS No.: 85262-50-6
• Molecular Formula: C8H7BrCl2O
• Molecular Weight: 269.953
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID00407050
• Wikidata: Q82212272
• Mol file: 85262-50-6.mol

Synonyms:2-(2-bromoethoxy)-1,4-dichlorobenzene;85262-50-6;2-(2-bromoethoxy)-1,4-dichloro-benzene;DTXSID00407050;AKOS000118318;CS-0233217;EN300-13180;Z94597999

Chemical Property of 2-(2-Bromoethoxy)-1,4-dichlorobenzene

Chemical Property:

• Vapor Pressure: 0.0014mmHg at 25°C
• Boiling Point: 306.4°C at 760 mmHg
• Flash Point: 139.1°C
• PSA: 9.23000
• Density: 1.616g/cm³
• LogP: 3.76710
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 267.90573
• Heavy Atom Count: 12
• Complexity: 134

Purity/Quality:

99% ^*data from raw suppliers

2-(2-BROMOETHOXY)-1,4-DICHLOROBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)OCCBr)Cl

Technology Process of 2-(2-Bromoethoxy)-1,4-dichlorobenzene

There total 1 articles about 2-(2-Bromoethoxy)-1,4-dichlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

2,5-dichlorophenol (583-78-8) + ethylene dibromide (106-93-4) → 1-bromo-2-(2,5-dichlorophenoxy)ethane (85262-50-6)

Guidance literature:

With sodium hydroxide; at 100 ℃; for 7h;

DOI:10.1021/jm030944+

Reference yield: 75.0%

1-bromo-2-(2,5-dichlorophenoxy)ethane (85262-50-6) + methylamine (74-89-5) → N-methyl-2-(2,5-dichlorophenoxy)ethylamine (688012-19-3)

Guidance literature:

In methanol; at 100 ℃; for 12h;

DOI:10.1021/jm030944+

Reference yield:

1-bromo-2-(2,5-dichlorophenoxy)ethane (85262-50-6) + 3-fluorobenzoyl chloride (1711-07-5) + tert-butyl 4-(aminomethyl)piperidine-1-carboxylate (144222-22-0) → C21H23Cl2FN2O2 (1414264-00-8)

Guidance literature:

tert-butyl 4-(aminomethyl)piperidine-1-carboxylate; With polystyrene carboxaldehyde resin; sodium cyanoborohydride; acetic acid; In N,N-dimethyl-formamide; at 60 ℃; for 24h; BAL-MBHA-PS-resin

3-fluorobenzoyl chloride; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h; BAL-MBHA-PS-resin

1-bromo-2-(2,5-dichlorophenoxy)ethane; Further stages;

DOI:10.1016/j.ejmech.2012.07.043 DOI:10.1016/j.ejmech.2012.07.043

upstream raw materials:

2,5-dichlorophenol

ethylene dibromide

Downstream raw materials:

1-(2,4-dichloro-phenoxy)-2-(2,5-dichloro-phenoxy)-ethane

1-(2,5-dichloro-phenoxy)-2-(2,4,6-trichloro-phenoxy)-ethane

N-<2-(2.5-Dichlorphenoxy)-ethyl>-cyclopropylamin

N-methyl-2-(2,5-dichlorophenoxy)ethylamine