((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone

Base Information

• Chemical Name: ((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone
• CAS No.: 1238824-54-8
• Molecular Formula: C₂₂H₃₂N₈O₅S₂
• Molecular Weight: 552.679
• Mol file: 1238824-54-8.mol

Synonyms:((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone

Chemical Property of ((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone

There total 1 articles about ((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H22N8O6 (1238824-46-8) + ethanethiol (75-08-1) → ((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone (1238824-54-8)

Guidance literature:

C₁₈H₂₂N₈O₆; ethanethiol; In dichloromethane; for 0.5h;

With chloro-trimethyl-silane; In dichloromethane; for 12h;

DOI:10.1016/j.tet.2010.05.003

Reference yield: 88.0%

(2S)-N-[5-methoxy-4-(2-propynyloxy)-2-nitrobenzoyl]-pyrrolidine-2-carboxaldehyde diethyl-dithioacetal (1037070-06-6) + ((2S,4S)-4-azido-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)(4-(5-azidopentyloxy)-5-methoxy-2-nitrophenyl)methanone (1238824-54-8) → (4-((1-((3S,5S)-5-(bis(ethylthio)methyl)-1-(4-(5-(4-((4-((S)-2-(bis(ethylthio)methyl)pyrrolidine-1-carbonyl)-2-methoxy-5-nitro-phenoxy)methyl)-1H-1,2,3-triazol-1-yl)pentyloxy)-5-methoxy-2-nitrobenzoyl)pyrrolidin-3-yl)-1H-1,2,3-triazol-4-yl)methoxy)-5-methoxy-2-nitrophenyl)((S)-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)methanone (1238824-62-8)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; for 12h;

DOI:10.1016/j.tet.2010.05.003

upstream raw materials:

C₁₈H₂₂N₈O₆

ethanethiol

Downstream raw materials:

(4-((1-((3S,5S)-5-(bis(ethylthio)methyl)-1-(4-(5-(4-((4-((S)-2-(bis(ethylthio)methyl)pyrrolidine-1-carbonyl)-2-methoxy-5-nitro-phenoxy)methyl)-1H-1,2,3-triazol-1-yl)pentyloxy)-5-methoxy-2-nitrobenzoyl)pyrrolidin-3-yl)-1H-1,2,3-triazol-4-yl)methoxy)-5-methoxy-2-nitrophenyl)((S)-2-(bis(ethylthio)methyl)pyrrolidin-1-yl)methanone