2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester
CAS No.:117326-00-8
Molecular Formula:C₄₄H₅₄O₁₁
Molecular Weight:758.906
Hs Code.:

2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Synonyms:2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Suppliers and Price of 2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

There total 10 articles about 2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3282-30-2
pivaloyl chloride

: 117326-00-8
2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 98 percent / pyridine / DMAP / CH₂Cl₂ / Ambient temperature

2: 1.) HgCl₂, CdCO₃, 2.) NaBH₃CN, further reducing agent and solvent / 1.) acetone-water, 2.) dimethoxyethane

3: 97 percent / silver perchlorate, 4-Angstroem molecular sieves / acetonitrile / -40 °C

4: 2.) pyridine

5: Bu₄NI, DMAP, diisopropylethylamine / tetrahydrofuran / 96 h / Ambient temperature

6: tetra-n-butylammonium fluoride

With pyridine; dmap; cadmium(II) carbonate; 4 A molecular sieve; tetrabutyl ammonium fluoride; silver perchlorate; tetra-(n-butyl)ammonium iodide; sodium cyanoborohydride; N-ethyl-N,N-diisopropylamine; mercury dichloride; dmap; In tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1016/S0040-4039(00)80342-1

Reference yield:

: 225797-51-3
(2R,3R,4R)-2,3,4-Trihydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxy]-pentanal

: 117326-00-8
2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: sodium hydride / dimethylformamide

2: p-toluenesulfonic acid / methanol

3: 98 percent / pyridine / DMAP / CH₂Cl₂ / Ambient temperature

4: 1.) HgCl₂, CdCO₃, 2.) NaBH₃CN, further reducing agent and solvent / 1.) acetone-water, 2.) dimethoxyethane

5: 97 percent / silver perchlorate, 4-Angstroem molecular sieves / acetonitrile / -40 °C

6: 2.) pyridine

7: Bu₄NI, DMAP, diisopropylethylamine / tetrahydrofuran / 96 h / Ambient temperature

8: tetra-n-butylammonium fluoride

With pyridine; dmap; cadmium(II) carbonate; 4 A molecular sieve; tetrabutyl ammonium fluoride; silver perchlorate; tetra-(n-butyl)ammonium iodide; sodium hydride; sodium cyanoborohydride; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; mercury dichloride; dmap; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/S0040-4039(00)80342-1

Reference yield:

: 117325-94-7
5-O-[(4-Methoxyphenyl)diphenylmethyl]-2,3,4-tris-O-(phenylmethyl)-D-ribose-diethyldithioacetal

: 117326-00-8
2,2-Dimethyl-propionic acid (2R,3S,4S)-2,3,4-tris-benzyloxy-5-((2R,3R,4R,5R)-3-benzyloxymethoxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-pentyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: p-toluenesulfonic acid / methanol

2: 98 percent / pyridine / DMAP / CH₂Cl₂ / Ambient temperature

3: 1.) HgCl₂, CdCO₃, 2.) NaBH₃CN, further reducing agent and solvent / 1.) acetone-water, 2.) dimethoxyethane

4: 97 percent / silver perchlorate, 4-Angstroem molecular sieves / acetonitrile / -40 °C

5: 2.) pyridine

6: Bu₄NI, DMAP, diisopropylethylamine / tetrahydrofuran / 96 h / Ambient temperature

7: tetra-n-butylammonium fluoride

With pyridine; dmap; cadmium(II) carbonate; 4 A molecular sieve; tetrabutyl ammonium fluoride; silver perchlorate; tetra-(n-butyl)ammonium iodide; sodium cyanoborohydride; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; mercury dichloride; dmap; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;
DOI:10.1016/S0040-4039(00)80342-1