Tris(2-chloroethyl) phosphite

Base Information

• Chemical Name: Tris(2-chloroethyl) phosphite
• CAS No.: 140-08-9
• Molecular Formula: C6H12 Cl3 O3 P
• Molecular Weight: 269.492
• Hs Code.: 2920901900
• European Community (EC) Number: 205-397-6
• NSC Number: 6514
• UN Number: 2810
• UNII: 66XM91RPZK
• DSSTox Substance ID: DTXSID0026258
• Nikkaji Number: J12.974G
• Wikidata: Q27264030
• ChEMBL ID: CHEMBL168105
• Mol file: 140-08-9.mol

Synonyms:TRIS(2-CHLOROETHYL) PHOSPHITE;140-08-9;Tris(2-chloroethyl)phosphite;Ethanol, 2-chloro-, phosphite (3:1);Phosphorous acid, tris(2-chloroethyl) ester;2-Chloroethanol phosphite (3:1);NSC 6514;Ethanol, 2-chloro-, 1,1',1''-phosphite;CCRIS 5949;Tris(beta-chloroethyl) phosphite;HSDB 2584;Tris(2-chloroethyl)ester of phosphorus acid;Tris(.beta.-chloroethyl) phosphite;EINECS 205-397-6;UNII-66XM91RPZK;Tris(chloroethyl) phosphite;BRN 1704979;66XM91RPZK;DTXSID0026258;NSC-6514;4-01-00-01378 (Beilstein Handbook Reference);DTXCID706258;CAS-140-08-9;C6H12Cl3O3P;Phosphorous Acid Tris(2-chloroethyl) Ester;Ethanol, phosphite (3:1);Tris 2-chloroethyl phosphite;SCHEMBL270154;tri-(2-chloroethyl) phosphite;2-chloroethanolphosphite(3:1);CHEMBL168105;tris (2-chloroethyl) phosphite;tris-(2-chloroethyl)-phosphite;Tris-(2-chloroethyl) phosphite;LUVCTYHBTXSAMX-UHFFFAOYSA-;tris-(2-chloro-ethyl) phosphite;NSC6514;tris (beta-chloroethyl) phosphite;Tox21_202136;Tox21_303066;LS-816;MFCD00000968;Phosphorous acid tris(2-chloroethyl);Tris(2-chloroethyl) phosphite, 85%;Tris(2-chloroethyl) phosphite, 97%;AKOS015916045;NCGC00091270-01;NCGC00091270-02;NCGC00257043-01;NCGC00259685-01;Tris(chloroethyl) Phosphite (85per cent);CS-0266566;FT-0700603;P0277;TRIS(2-CHLOROETHYL) PHOSPHITE [HSDB];D91938;EN300-1425567;J-007353;Q27264030

Chemical Property of Tris(2-chloroethyl) phosphite

Chemical Property:

• Vapor Pressure: 0.00359mmHg at 25°C
• Refractive Index: n20/D 1.487(lit.)
• Boiling Point: 290.5°Cat760mmHg
• Flash Point: 97.2°C
• PSA: 41.28000
• Density: g/cm³
• LogP: 2.97950
• Storage Temp.: -20°C
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 267.958964
• Heavy Atom Count: 13
• Complexity: 90.1
• Transport DOT Label: Poison

Purity/Quality:

97% ^*data from raw suppliers

Tris(chloroethyl)Phosphite(85%) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 45-21-25-36/37/38-23/24/25-46
• Safety Statements: 53-26-36/37/39-45-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Organophosphates, Other
• Canonical SMILES: C(CCl)OP(OCCCl)OCCCl

Technology Process of Tris(2-chloroethyl) phosphite

There total 7 articles about Tris(2-chloroethyl) phosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

oxirane (75-21-8,99932-75-9) → tris(2-chloro-ethyl)phosphite (140-08-9)

Guidance literature:

With phosphorus trichloride; at 10 - 15 ℃; for 0.0347222h; under 2250.23 Torr; Temperature; Pressure; Flow reactor;

Reference yield: 73.0%

2-chloro-ethanol (107-07-3) → tris(2-chloro-ethyl)phosphite (140-08-9)

Guidance literature:

With potassium phosphate; tetrahexylammonium chloride; phosphorus trichloride; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1002/hc.20438

Reference yield:

2-chloro-ethanol (107-07-3) → bis(β-chloroethyl) chlorophosphite (37984-64-8) + tris(2-chloro-ethyl)phosphite (140-08-9)

Guidance literature:

With oxirane; triethylamine; phosphorus trichloride; at 40 - 60 ℃; for 5h; Concentration;

upstream raw materials:

oxirane

pyridine

diethyl ether

dichloro-(2-chloroethoxy)-phosphine

Downstream raw materials:

bis(2-chloroethyl) methylphosphonate

{[Bis-(2-chloro-ethoxy)-phosphanyloxy]-phenyl-methyl}-phosphonic acid bis-(2-chloro-ethyl) ester

[1-(Diphenoxy-phosphanyloxy)-ethyl]-phosphonic acid bis-(2-chloro-ethyl) ester

{(E)-1-[Bis-(2-chloro-ethoxy)-phosphanyloxy]-3-phenyl-allyl}-phosphonic acid bis-(2-chloro-ethyl) ester