(R)-2-(4-bromophenyl)-2-cyclopropylpropanal

Base Information

Chemical Name:(R)-2-(4-bromophenyl)-2-cyclopropylpropanal
CAS No.:1448893-30-8
Molecular Formula:C₁₂H₁₃BrO
Molecular Weight:253.139
Hs Code.:

Synonyms:(R)-2-(4-bromophenyl)-2-cyclopropylpropanal

Suppliers and Price of (R)-2-(4-bromophenyl)-2-cyclopropylpropanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-2-(4-bromophenyl)-2-cyclopropylpropanal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2-(4-bromophenyl)-2-cyclopropylpropanal

There total 5 articles about (R)-2-(4-bromophenyl)-2-cyclopropylpropanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-09-2
dichloromethane

: (S)-2-(1-(4-bromophenyl)-1-cyclopropylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1448893-30-8
(R)-2-(4-bromophenyl)-2-cyclopropylpropanal

Guidance literature:: dichloromethane; (S)-2-(1-(4-bromophenyl)-1-cyclopropylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; With lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; n-heptane; ethylbenzene; at -45 - 40 ℃; Inert atmosphere; Large scale;

With methanol; In tetrahydrofuran; 1,4-dioxane; n-heptane; ethylbenzene; at -45 - 20 ℃; Inert atmosphere; Large scale;

With dihydrogen peroxide; In tetrahydrofuran; 1,4-dioxane; n-heptane; ethylbenzene; water; at 0 - 25 ℃; Solvent; Temperature; Time; Reagent/catalyst; Inert atmosphere; Large scale;

Reference yield:

: (S)-2-(1-(4-bromophenyl)-1-cyclopropylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1448893-30-8
(R)-2-(4-bromophenyl)-2-cyclopropylpropanal

Guidance literature:: With dihydrogen peroxide; In water; at 20 ℃; for 0.5h; Solvent; Temperature; Reagent/catalyst; Inert atmosphere;
DOI:10.1021/jo502550h

Reference yield:

: 99-90-1
para-bromoacetophenone

: 1448893-30-8
(R)-2-(4-bromophenyl)-2-cyclopropylpropanal

Guidance literature:: Multi-step reaction with 4 steps

1.1: formic acid; N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide; dichloro(mesitylene)ruthenium(II) dimer; triethylamine / acetonitrile / 15 h / 0 - 20 °C / Inert atmosphere; Large scale

2.1: triethylamine / acetonitrile / 18 h / 82 °C / Inert atmosphere; Large scale

3.1: lithium diisopropyl amide / tert-butyl methyl ether / -15 - 10 °C / Inert atmosphere; Large scale

4.1: lithium diisopropyl amide / tetrahydrofuran; 1,4-dioxane; n-heptane; ethylbenzene / -45 - 40 °C / Inert atmosphere; Large scale

4.2: -45 - 20 °C / Inert atmosphere; Large scale

4.3: 0 - 25 °C / Inert atmosphere; Large scale

With formic acid; dichloro(mesitylene)ruthenium(II) dimer; triethylamine; N-[(1S,2S)-2-amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; n-heptane; tert-butyl methyl ether; ethylbenzene; acetonitrile;