2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

Base Information

Chemical Name:2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester
CAS No.:73789-98-7
Molecular Formula:C₁₆H₁₄F₂O₂
Molecular Weight:276.283
Hs Code.:2918300090

Synonyms:2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

Suppliers and Price of 2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Ethyl 2-(4-biphenylyl)-2,2-difluoroacetate
1 g
$ 885.00

AK Scientific
Ethyl2-(4-Biphenylyl)-2,2-difluoroacetate
1g
$ 802.00

Total 3 raw suppliers

Chemical Property of 2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 2-(4-biphenylyl)-2,2-difluoroacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

There total 23 articles about 2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 667-27-6
Ethyl bromodifluoroacetate

: 92-66-0
4-bromo-1,1'-biphenyl

: 73789-98-7
2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

Guidance literature:: With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; tetrabutylammomium bromide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; zinc; In tetrahydrofuran; at 60 ℃; for 24h; Reagent/catalyst; Solvent; Inert atmosphere;
DOI:10.1021/acs.orglett.7b00938

Reference yield: 92.0%

: 6244-53-7
ethyl (4-phenylphenyl)glyoxylate

: 73789-98-7
2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

Guidance literature:: With diethylamino-sulfur trifluoride; 1) 45 deg C, 3) 2h, RT;
DOI:10.1021/jo01302a025

Reference yield: 87.0%

: 201230-82-2
carbon monoxide

: 667-27-6
Ethyl bromodifluoroacetate

: 5122-94-1
4-biphenylboronic acid

: ethyl 3-([1,1'-biphenyl]-4-yl)-2,2-difluoro-3-oxopropanoate

: 73789-98-7
2-([1,1'-biphenyl]-4-yl)-2,2-difluoroacetic acid ethyl ester

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; copper(II) hexafluoro-2,4-pentanedionate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 80 ℃; for 24h; under 760.051 Torr; Solvent; Reagent/catalyst; Schlenk technique; Molecular sieve; Inert atmosphere;
DOI:10.1002/anie.201605380