(3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate

Base Information

Chemical Name:(3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate
CAS No.:1218923-34-2
Molecular Formula:C₂₅H₃₀N₂O₃
Molecular Weight:406.525
Hs Code.:

Synonyms:(3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate

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Chemical Property of (3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate

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Technology Process of (3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate

There total 3 articles about (3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 123-75-1
pyrrolidine

: 1218923-24-0
2-(3-(N-benzotriazolcarbonyloxy)(phenyl)(methyl)phenyl) propanoic acid benzotriazolide

: 1218923-34-2
(3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate

Guidance literature:: With triethylamine; In toluene; at 20 ℃; for 0.5h;
DOI:10.1016/j.ejmech.2010.04.008

Reference yield:

: 59960-32-6
Dihydroketoprofen

: 1218923-34-2
(3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / toluene / 1 h / 20 °C

2: triethylamine / toluene / 0.5 h / 20 °C

With triethylamine; In toluene;
DOI:10.1007/s00044-010-9309-2

Reference yield:

: 22071-15-4,22161-86-0
ketoprofen

: 1218923-34-2
(3-(1-oxo-1-(pyrrolidin-1-yl)propan-2-yl)phenyl)(phenyl)methyl pyrrolidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: palladium on activated charcoal; hydrogen / tetrahydrofuran

2: triethylamine / toluene / 1 h / 20 °C

3: triethylamine / toluene / 0.5 h / 20 °C

With palladium on activated charcoal; hydrogen; triethylamine; In tetrahydrofuran; toluene;
DOI:10.1007/s00044-010-9309-2