Aldicarb

Base Information

• Chemical Name: Aldicarb
• CAS No.: 116-06-3
• Molecular Formula: C7H14 N2 O2 S
• Molecular Weight: 190.266
• Hs Code.: 29309090
• European Community (EC) Number: 204-123-2
• ICSC Number: 0094
• NSC Number: 379586
• UN Number: 2757
• Wikipedia: Aldicarb
• Wikidata: Q27285799
• NCI Thesaurus Code: C163578
• Metabolomics Workbench ID: 52947
• ChEMBL ID: CHEMBL91732
• Mol file: 116-06-3.mol

Synonyms:Aldicarb;ENT 27,093;ENT-27,093;ENT27,093;Temik;UC 21,149;UC 21149;UC-21,149;UC-21149;UC21,149;UC21149

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Chemical Property of Aldicarb

Chemical Property:

• Appearance/Colour: COLOURLESS CRYSTALS.
• Vapor Pressure: 1.3×10-2 Pa (25 °C)
• Melting Point: 100ºC
• Refractive Index: 1.492
• Boiling Point: °Cat760mmHg
• PKA: 11.7
• Flash Point: >100 ºC
• PSA: 75.99000
• Density: 1.08 g/cm³
• LogP: 1.86070
• Storage Temp.: APPROX 4°C
• Water Solubility.: 4.9 g l-1(pH 7,20 °C)
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 190.07759887
• Heavy Atom Count: 12
• Complexity: 180
• Transport DOT Label: Poison

Purity/Quality:

Safty Information:

• Hazard Codes: T+,N,Xn,F
• Statements: 24-26/28-50/53-36-20/21/22-11
• Safety Statements: 22-36/37-45-60-61-26-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Carbamate Insecticides
• Canonical SMILES: CC(C)(C=NOC(=O)NC)SC
• Isomeric SMILES: CC(C)(/C=N/OC(=O)NC)SC
• Inhalation Risk: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C; on spraying or dispersing, however, much faster.
• Effects of Short Term Exposure: The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. Cholinesterase inhibition. Exposure could cause death. The effects may be delayed. Medical observation is indicated.
• Description: Aldicarb is a carbamate pesticide that reversibly inhibits acetylcholinesterase. It is the active ingredient in mixtures used to control insect, mite, and nematode pests in agriculture. Aldicarb has a high acute mammalian toxicity (LD50 = 0.3-0.5 mg/kg) following oral or parenteral administration. Aside from its use as a pesticide, aldicarb has applications as an acetylcholinesterase inhibitor for research purposes.
• Uses: Aldicarb is a broad-spectrum, systemic carbamate insecticide used to control nema-todes in soil and a variety of insects and mites on citrus crops, dry beans, grain, sorghum, ornamentals, pecans, peanuts, potatoes, seed alfalfa, soybeans, sugar beets, sugarcane, sweet potatoes, and tobacco. Aldicarb is a soil applied systemic oxime carbamate insecticide with both contact and oral activities. It controls a broad spectrum of chewing and sucking insects, mites and nematodes on a wide variety of field, fruit and vegetables crops such as cotton, citrus, potatoes, sugar beet and peanuts.

Technology Process of Aldicarb

There total 4 articles about Aldicarb which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-2-methylsulfanyl-propionaldehyde oxime (1646-75-9) → temik (116-06-3)

Guidance literature:

Multi-step reaction with 2 steps

1: CHCl₃ / 2 h / Heating

2: CHCl₃ / 1 h / Ambient temperature

In chloroform;

DOI:10.1016/S0040-4039(01)81064-9

Reference yield:

C9H13N3O5S (119776-75-9) + methylamine (74-89-5) → temik (116-06-3) + 3,5-dioxo-4-methyl-1,2,4-oxadiazolidine (27268-68-4)

Guidance literature:

In chloroform; for 1h; Yield given; Ambient temperature;

DOI:10.1016/S0040-4039(01)81064-9

Reference yield:

carbonochloridic acid 1-chloro-ethyl ester (50893-53-3) + 2-methyl-2-methylsulfanyl-propionaldehyde oxime (1646-75-9) + methylamine (74-89-5) → temik (116-06-3)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1055/s-1986-31724

upstream raw materials:

carbonochloridic acid 1-chloro-ethyl ester

2-methyl-2-methylsulfanyl-propionaldehyde oxime

methylamine

C₉H₁₃N₃O₅S

Downstream raw materials:

carbon dioxide

2-methyl-2-methylsulfanyl-propionaldehyde oxime

methylamine

C₁₄H₁₈F₃N₃O₃S₂

Refernces

• 1、 Denarie, Michel,Grenouillat, Denis,Malfroot, Thierry,Senet, Jean-Pierre,Sennyey, Gerard,Wolf, Patrick. "2,2'-CARBONYL-BIS(3,5-DIOXO-4-METHYL-1,2,4-OXADIAZOLIDINE) : I- A NEW REAGENT FOR THE PREPARATION OF CARBAMATES AND AMIDES, APPLICATION TO THE SYNTHESIS OF DIPEPTIDES.". . p. 5823 - 5826. Retrieved 2007/10/02.