4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

Base Information

Chemical Name:4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde
CAS No.:1312698-60-4
Molecular Formula:C₂₁H₂₃BO₅
Molecular Weight:366.222
Hs Code.:

Synonyms:4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

Suppliers and Price of 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

There total 7 articles about 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.8%

: 3328-70-9
5-formyl-2-hydroxybenzaldehyde

: 138500-85-3
4-bromomethylphenylboronic acid pinacol ester

: 1312698-60-4
4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

Guidance literature:: 4-bromomethylphenylboronic acid pinacol ester; With caesium carbonate; In acetonitrile; at 60 ℃; for 0.333333h;

5-formyl-2-hydroxybenzaldehyde; With potassium iodide; at 60 ℃; for 24h; Darkness;
DOI:10.1039/c9cc07768e

Reference yield: 66.0%

: 1169945-44-1
2-(4-(iodomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 3328-70-9
5-formyl-2-hydroxybenzaldehyde

: 1312698-60-4
4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

Guidance literature:: 5-formyl-2-hydroxybenzaldehyde; With potassium carbonate; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;

2-(4-(iodomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In N,N-dimethyl-formamide; at 20 ℃; for 12h;
DOI:10.1021/ja203145v

Reference yield:

: 302348-51-2
(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol

: 1312698-60-4
4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)benzyl)oxy)benzene-1,3-dicarbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium iodide; chloro-trimethyl-silane / acetonitrile / 1 h / 0 - 20 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.33 h

2.2: 20 °C

With chloro-trimethyl-silane; potassium carbonate; sodium iodide; In N,N-dimethyl-formamide; acetonitrile;