4,5-Dimethyloxazol-2-amine

Base Information

• Chemical Name: 4,5-Dimethyloxazol-2-amine
• CAS No.: 45529-92-8
• Molecular Formula: C5H8 N2 O
• Molecular Weight: 112.131
• Hs Code.: 2934999090
• European Community (EC) Number: 256-241-9
• DSSTox Substance ID: DTXSID10196549
• Nikkaji Number: J829.598K
• Wikidata: Q72436310
• Mol file: 45529-92-8.mol

Synonyms:4,5-Dimethyloxazol-2-amine;45529-92-8;4,5-Dimethyl-1,3-oxazol-2-amine;2-Oxazolamine, 4,5-dimethyl-;DIMETHYL-1,3-OXAZOL-2-AMINE;EINECS 256-241-9;2-Amino-4,5-dimethyloxazole;4,5-Dimethyl-oxazol-2-ylamine;2-Amino-4,5-dimethyl-oxazole;SCHEMBL1100800;DTXSID10196549;HMS1767H14;MFCD06655295;AKOS000123004;AB25421;4,5-Dimethyl-1,3-oxazol-2-amine #;BS-12793;FT-0698428;EN300-12322;4,5-dimethyl-1,3-oxazol-2-amine, AldrichCPR;A20382;F16841;J-514102;Z85932429

Chemical Property of 4,5-Dimethyloxazol-2-amine

Chemical Property:

• Vapor Pressure: 0.0742mmHg at 25°C
• Melting Point: 78-79℃ (benzene )
• Boiling Point: 228.3°Cat760mmHg
• PKA: 6.45±0.14(Predicted)
• Flash Point: 91.8°C
• PSA: 52.05000
• Density: 1.118g/cm³
• LogP: 1.45480
• Storage Temp.: 2-8°C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 112.063662883
• Heavy Atom Count: 8
• Complexity: 86.5

Purity/Quality:

97% ^*data from raw suppliers

4,5-Dimethyloxazol-2-amine ^*data from reagent suppliers

Safty Information:

• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(OC(=N1)N)C

Technology Process of 4,5-Dimethyloxazol-2-amine

There total 6 articles about 4,5-Dimethyloxazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

3-chloro-2-butanone (4091-39-8) + urea (57-13-6) → 2-amino-4,5-dimethyloxazole (45529-92-8)

Guidance literature:

In isopropyl alcohol; for 0.0833333h; Reflux;

Reference yield:

CYANAMID (420-04-2) + 3-hydroxy-2-butanon (513-86-0,52217-02-4,51555-24-9) → 2-amino-4,5-dimethyloxazole (45529-92-8)

Guidance literature:

CYANAMID; 3-hydroxy-2-butanon; In water; at 45 - 50 ℃; for 0.5h;

With sodium hydroxide; In water; at 17 - 25 ℃; pH=10;

Reference yield:

urea (57-13-6) + 3-bromo-butanone (814-75-5) → 2-amino-4,5-dimethyloxazole (45529-92-8)

Guidance literature:

With N,N-dimethyl-formamide;

upstream raw materials:

urea

3-bromo-butanone

(4,5-dimethyl-oxazol-2-yl)-cyanamide

CYANAMID

Downstream raw materials:

sulphamoxole

6-(4-Chloro-phenyl)-2,3-dimethyl-imidazo[2,1-b]oxazole

1-(3-chloro-phenyl)-3-(4,5-dimethyl-oxazol-2-yl)-urea