Technology Process of (E)-dibenzyl 2-benzylfumarate
There total 3 articles about (E)-dibenzyl 2-benzylfumarate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
phthalimide; di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran;
at 20 ℃;
for 3h;
DOI:10.1016/j.tetasy.2012.01.004
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 1 h / -78 °C / Inert atmosphere
1.3: 20 °C / Inert atmosphere
2.1: phthalimide; di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 3 h / 20 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; phthalimide; di-isopropyl azodicarboxylate; triphenylphosphine; lithium hexamethyldisilazane;
In
tetrahydrofuran;
2.1: Mitsunobu dehydration;
DOI:10.1016/j.tetasy.2012.01.004
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N,N,N,N,N,N-hexamethylphosphoric triamide; lithium hexamethyldisilazane / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere
1.2: 1 h / -78 °C / Inert atmosphere
1.3: 20 °C / Inert atmosphere
2.1: phthalimide; di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 3 h / 20 °C
With
N,N,N,N,N,N-hexamethylphosphoric triamide; phthalimide; di-isopropyl azodicarboxylate; triphenylphosphine; lithium hexamethyldisilazane;
In
tetrahydrofuran;
2.1: Mitsunobu dehydration;
DOI:10.1016/j.tetasy.2012.01.004
