Ethyl n-[2-(diethylamino)ethyl]glycinate

Base Information

• Chemical Name: Ethyl n-[2-(diethylamino)ethyl]glycinate
• CAS No.: 7568-71-0
• Molecular Formula: C₁₀H₂₂N₂O₂
• Molecular Weight: 202.297
• NSC Number: 158986
• DSSTox Substance ID: DTXSID30997111
• Wikidata: Q82989103
• Mol file: 7568-71-0.mol

Synonyms:7568-71-0;ethyl n-[2-(diethylamino)ethyl]glycinate;NSC158986;SCHEMBL15654046;DTXSID30997111;AKOS000255990;NSC-158986;EN300-8512613;ETHYL 2-{[2-(DIETHYLAMINO)ETHYL]AMINO}ACETATE

Chemical Property of Ethyl n-[2-(diethylamino)ethyl]glycinate

Chemical Property:

• Vapor Pressure: 0.00976mmHg at 25°C
• Boiling Point: 264.4°C at 760 mmHg
• Flash Point: 113.7°C
• Density: 0.949g/cm³
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 202.168127949
• Heavy Atom Count: 14
• Complexity: 147

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CCNCC(=O)OCC

Technology Process of Ethyl n-[2-(diethylamino)ethyl]glycinate

There total 2 articles about Ethyl n-[2-(diethylamino)ethyl]glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glyoxylic acid ethyl ester (924-44-7) + N,N-diethylethylenediamine (100-36-7) → N-<2-Diaethylamino-aethyl>-glycin-aethylester (7568-71-0)

Guidance literature:

glyoxylic acid ethyl ester; N,N-diethylethylenediamine; In ethanol; toluene; at 20 ℃; for 1h;

With sodium cyanoborohydride; acetic acid; In ethanol; toluene; for 2h;

With sodium chloride; sodium hydroxide;

DOI:10.1016/j.tet.2010.01.090

Reference yield:

ethyl bromoacetate (105-36-2) + N,N-diethylethylenediamine (100-36-7) → N-<2-Diaethylamino-aethyl>-glycin-aethylester (7568-71-0)

Guidance literature:

In benzene;

DOI:10.1021/jo01075a014

upstream raw materials:

ethyl bromoacetate

N,N-diethylethylenediamine

glyoxylic acid ethyl ester