Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate

Base Information

Chemical Name:Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate
CAS No.:77995-07-4
Molecular Formula:C₁₉H₁₆N₂O₂
Molecular Weight:304.348
Hs Code.:
DSSTox Substance ID:DTXSID401264712
Nikkaji Number:J284.692F
ChEMBL ID:CHEMBL1579800
Mol file:77995-07-4.mol

Synonyms:ethyl 2,4-diphenyl-5-pyrimidinecarboxylate;77995-07-4;ethyl 2,4-diphenylpyrimidine-5-carboxylate;MLS000692207;CHEMBL1579800;DTXSID401264712;HMS2646M08;MFCD00215423;AKOS005082567;1J-510S;ethyl2,4-diphenylpyrimidine-5-carboxylate;SMR000333873;2,4-Diphenylpyrimidine-5-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate
5g
$ 7343.00

Matrix Scientific
Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate
1g
$ 1836.00

Matrix Scientific
Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate
500mg
$ 918.00

American Custom Chemicals Corporation
ETHYL 2,4-DIPHENYL-5-PYRIMIDINECARBOXYLATE 95.00%
5MG
$ 623.82

American Custom Chemicals Corporation
ETHYL 2,4-DIPHENYL-5-PYRIMIDINECARBOXYLATE 95.00%
10MG
$ 618.50

American Custom Chemicals Corporation
ETHYL 2,4-DIPHENYL-5-PYRIMIDINECARBOXYLATE 95.00%
1MG
$ 586.97

Total 1 raw suppliers

Chemical Property of Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:304.121177757
Heavy Atom Count:23
Complexity:376

Purity/Quality:: Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=CN=C(N=C1C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate

There total 4 articles about Ethyl 2,4-diphenyl-5-pyrimidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 53256-19-2
ethyl (Z)-3-amino-3-phenylacrylate

: 55-21-0,27208-38-4
benzamide

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 77995-07-4
ethyl 2,4-diphenylpyrimidine-5-carboxylate

Guidance literature:: benzamide; N,N-dimethyl-formamide dimethyl acetal; In 1,2-dichloro-ethane; at 60 ℃; Sealed tube;

ethyl (Z)-3-amino-3-phenylacrylate; With copper diacetate; In 1,2-dichloro-ethane; at 100 ℃; regioselective reaction; Molecular sieve;
DOI:10.1002/adsc.201700234

Reference yield: 68.0%

: 5720-07-0
4-methoxyphenylboronic acid

: C₁₇H₂₂N₂O₂S

: 77995-07-4
ethyl 2,4-diphenylpyrimidine-5-carboxylate

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; copper(I) thiophene-2-carboxylate; In toluene; at 100 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2017.10.010