(2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

Base Information

Chemical Name:(2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal
CAS No.:136786-40-8
Molecular Formula:C₂₆H₃₈O₄Si
Molecular Weight:442.671
Hs Code.:

Synonyms:(2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

Suppliers and Price of (2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

There total 7 articles about (2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 910043-08-2
6-(tert-butyldiphenylsilyloxy)-3(S),5(S)-dimethyl-2(S)-(methoxymethoxy)hexan-1-ol

: 136786-40-8
(2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 20 ℃; for 0.666667h;
DOI:10.1021/ja0581346

Reference yield:

: 136786-39-5
benzyl [6-(tert-butyldiphenylsilyloxy)-3(S),5(S)-dimethyl-2(S)-(methoxymethoxy)hex-1-yl] ether

: 136786-40-8
(2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / hydrogen / Pd/C / ethanol / 760 Torr

2: 100 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / 0.67 h / -78 - 20 °C

With oxalyl dichloride; hydrogen; dimethyl sulfoxide; triethylamine; palladium on activated charcoal; In ethanol; dichloromethane; 2: Swern oxidation;
DOI:10.1021/ja0581346

Reference yield:

: 136786-36-2
(2S,3S,5S)-1-(benzyloxy)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethylhexan-2-ol

: 136786-40-8
(2S,3S,5S)-6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-(methoxymethoxy)hexanal

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / iPr₂NEt; TBAI / CH₂Cl₂ / 48 h / 20 °C

2: 86 percent / hydrogen / Pd/C / ethanol / 760 Torr

3: 100 percent / oxalyl chloride; DMSO; triethylamine / CH₂Cl₂ / 0.67 h / -78 - 20 °C

With oxalyl dichloride; hydrogen; tetra-(n-butyl)ammonium iodide; dimethyl sulfoxide; triethylamine; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In ethanol; dichloromethane; 3: Swern oxidation;
DOI:10.1021/ja0581346