1,1,4,7,10,10-Hexamethyltriethylenetetramine

Base Information

• Chemical Name: 1,1,4,7,10,10-Hexamethyltriethylenetetramine
• CAS No.: 3083-10-1
• Molecular Formula: C12H30 N4
• Molecular Weight: 230.397
• Hs Code.: 29212900
• European Community (EC) Number: 221-382-7
• NSC Number: 166488
• UNII: 0OAF7T9SCQ
• DSSTox Substance ID: DTXSID6062836
• Nikkaji Number: J217.245C
• Wikidata: Q72482181
• Pharos Ligand ID: GQ2MRK3P6LBZ
• ChEMBL ID: CHEMBL1214194
• Mol file: 3083-10-1.mol

Synonyms:1,1,4,7,10,10-Hexamethyltriethylenetetramine;HMTTA cpd

Chemical Property of 1,1,4,7,10,10-Hexamethyltriethylenetetramine

Chemical Property:

• Vapor Pressure: 0.0123mmHg at 25°C
• Melting Point: 162 °C
• Refractive Index: n20/D 1.456(lit.)
• Boiling Point: 260.4°Cat760mmHg
• PKA: 8.83±0.38(Predicted)
• Flash Point: 101.7°C
• PSA: 12.96000
• Density: 0.901g/cm³
• LogP: -0.02680
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility.: Soluble in water.
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 9
• Exact Mass: 230.24704697
• Heavy Atom Count: 16
• Complexity: 141

Purity/Quality:

99% ^*data from raw suppliers

N1,N1''-(Ethane-1,2-diyl)bis(N1,N2,N2-trimethylethane-1,2-diamine) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,C
• Statements: 36/37/38-34
• Safety Statements: 26-37/39-45-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCN(C)CCN(C)CCN(C)C
• Uses: 1,1,4,7,10,10-Hexamethyltriethylenetetramine may be used as reagent in the synthesis of ideal linear random copolymers containing both vinyl polymer and polyester units in a single polymer chain. 1,1,4,7,10,10-Hexamethyltriethylenetetramine complexed with CuBr constitutes catalytic complex, used in the copolymerization of poly[ε-caprolactone] with N,N-dimethylamino-2-ethyl methacrylate monomers by atom-transfer radical polymerization (ATRP). It may be used as catalyst in the aqueous surface-initiated-ATRP to grow poly(N,N-dimethylacrylamide) (PDMA). suzuki reaction

Technology Process of 1,1,4,7,10,10-Hexamethyltriethylenetetramine

There total 9 articles about 1,1,4,7,10,10-Hexamethyltriethylenetetramine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + triethylentetramine (112-24-3) → 1,1,4,7,10,10-hexamethyltriethylenetetramine (3083-10-1)

Guidance literature:

With formic acid; for 24h; Heating;

DOI:10.1039/DT9880002885

Reference yield:

1,1,4,7,10,10-hexamethyltriethylenetetramine and lithium picrate complex → 1,1,4,7,10,10-hexamethyltriethylenetetramine (3083-10-1)

Guidance literature:

With RG₇; In toluene; at 25 ℃; Equilibrium constant;

DOI:10.1021/ja00325a013

Reference yield:

-sarkosyl-sarkosin-dimethylamid (13574-25-9) → 1,1,4,7,10,10-hexamethyltriethylenetetramine (3083-10-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

upstream raw materials:

formaldehyd

triethylentetramine

-sarkosyl-sarkosin-dimethylamid

formic acid

Downstream raw materials:

FENVALERATE

N,N,N',N'',N'''-pentamethyldiethylenetriamine

1,4,8,11-tetramethyl-1,4,8,11-tetra-azacyclotetradecane

cis-[(hmteta)Ca(PPh₂)2]

Refernces

• 1、 Golub, Gilad,Cohen, Haim,Paoletti, Piero,Bencin, Andrea,Meyerstein, Dan. "Copper-(I) and -(II) complexes with tertiary linear polyamines of the type Me2NCH2(CH2NMeCH2) nCH2NMe2 (n = 1-4)". . p. 2055 - 2060. Retrieved 1996.
• 2、 Tang, Hui. "Coordination to RMg+ and RZn+ cations". . p. 4810 - 4819. Retrieved 2008/10/08.