(2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

Base Information

Chemical Name:(2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate
CAS No.:1379613-66-7
Molecular Formula:C₄₃H₄₅NO₁₂
Molecular Weight:767.83
Hs Code.:

Synonyms:(2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

Suppliers and Price of (2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

There total 6 articles about (2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58570-06-2
2-(benzoyloxy)-2-methylpropanoic acid chloride

: 37169-37-2
(2S)-benzyl 2-((tert-butoxycarbonyl)amino)-3-(3,4-dihydroxyphenyl)propanoate

: 1379613-66-7
(2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

Guidance literature:: With triethylamine; In acetonitrile; for 1.25h; Cooling with ice; Inert atmosphere;

Reference yield:

: 58570-00-6
2-(benzoyloxy)-2-methylpropanoic acid

: 1379613-66-7
(2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; thionyl chloride / toluene / 1 h / 70 °C / Inert atmosphere

2: triethylamine / acetonitrile / 1.25 h / Cooling with ice; Inert atmosphere

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In toluene; acetonitrile;

Reference yield:

: 59-92-7,90638-38-3
levodopa

: 1379613-66-7
(2S)-((4-(3-benzyloxy)-2-((tert-butoxycarbonyl)amino)-3-oxopropyl-1,2-phenylene)bis(oxy))bis(2-methyl-1-oxopropan-2,1-diyl)dibenzoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / water; tetrahydrofuran / 14 h / 20 °C / Inert atmosphere

1.2: Cooling with ice

2.1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 7 h / 20 °C / Inert atmosphere

3.1: triethylamine / acetonitrile / 1.25 h / Cooling with ice; Inert atmosphere

With potassium hydrogencarbonate; triethylamine; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetonitrile;