benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate

Base Information

Chemical Name:benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate
CAS No.:1401791-62-5
Molecular Formula:C₃₈H₃₉NO₆
Molecular Weight:605.731
Hs Code.:

Synonyms:benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate

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Chemical Property of benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate

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Technology Process of benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate

There total 5 articles about benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1259391-04-2
benzyl 2-propoxy-5-formylsalicylate

: 1401791-62-5
benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tetrahydroborate / ethanol / 0 - 20 °C

2: phosphorus tribromide / diethyl ether / 2 h / 0 °C

3: sodium hexamethyldisilazane / tetrahydrofuran / -50 - -15 °C / Inert atmosphere

With sodium tetrahydroborate; sodium hexamethyldisilazane; phosphorus tribromide; In tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1016/j.bmc.2012.08.061

Reference yield:

: 176047-66-8
benzyl 2-hydroxy-5-formylbenzoate

: 1401791-62-5
benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 60 °C

2: sodium tetrahydroborate / ethanol / 0 - 20 °C

3: phosphorus tribromide / diethyl ether / 2 h / 0 °C

4: sodium hexamethyldisilazane / tetrahydrofuran / -50 - -15 °C / Inert atmosphere

With sodium tetrahydroborate; sodium hexamethyldisilazane; phosphorus tribromide; potassium carbonate; In tetrahydrofuran; diethyl ether; ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2012.08.061

Reference yield:

: 1259391-05-3
benzyl 5-hydroxymethyl-2-propoxybenzoate

: 1401791-62-5
benzyl 5-((R)-2-benzyl-3-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-3-oxopropyl)-2-propoxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: phosphorus tribromide / diethyl ether / 2 h / 0 °C

2: sodium hexamethyldisilazane / tetrahydrofuran / -50 - -15 °C / Inert atmosphere

With sodium hexamethyldisilazane; phosphorus tribromide; In tetrahydrofuran; diethyl ether;
DOI:10.1016/j.bmc.2012.08.061