Technology Process of C14H18FNO3
There total 4 articles about C14H18FNO3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-(cyclopentyloxy)-4-fluorobenzoic acid;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.0833333h;
N,O-dimethylhydroxylamine*hydrochloride;
With
triethylamine;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 13h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sulfuric acid / 4 h / 105 °C
2.1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 125 °C
3.1: water; sodium hydroxide / ethanol / 3 h / 55 °C
4.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 20 °C
4.2: 13 h / 20 °C
With
sulfuric acid; water; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide;
In
ethanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 125 °C
2.1: water; sodium hydroxide / ethanol / 3 h / 55 °C
3.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.08 h / 20 °C
3.2: 13 h / 20 °C
With
water; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; sodium hydroxide;
In
ethanol; N,N-dimethyl-formamide;
