2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

Base Information

Chemical Name:2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline
CAS No.:502481-64-3
Molecular Formula:C₁₉H₂₉N₃O₅
Molecular Weight:379.456
Hs Code.:

Synonyms:2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

Suppliers and Price of 2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

There total 8 articles about 2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 502481-63-2
2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylnitrobenzene

: 502481-64-3
2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

Guidance literature:: With hydrogen; 10 percent Pd/C contd. 50 percent water; In ethyl acetate; at 20 ℃; atmospheric pressure;
DOI:10.1021/jm020239l

Reference yield:

: 61161-83-9
5-(hydroxymethyl)-2-nitrophenol

: 502481-64-3
2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

Guidance literature:: Multi-step reaction with 6 steps

1: K₂CO₃ / dimethylformamide / 50 °C

2: Et₃N / CH₂Cl₂ / 0 °C

3: dimethylformamide / 20 °C

4: N₂H₄*H₂O; p-TsOH*H₂O / tetrahydrofuran / Heating

5: ethyl acetate / 20 °C

6: H₂ / 10 percent Pd/C contd. 50 percent water / ethyl acetate / 20 °C / atmospheric pressure

With hydrogen; potassium carbonate; toluene-4-sulfonic acid; hydrazine hydrate; triethylamine; 10 percent Pd/C contd. 50 percent water; In tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm020239l

Reference yield:

: 619-14-7
3-hydroxy-4-nitro-benzoic acid

: 502481-64-3
2-((S)-1-morpholinocarbonylethoxy)-4-tert-butoxycarbonylaminomethylaniline

Guidance literature:: Multi-step reaction with 7 steps

1: 94 percent / (MeO)3B; BF₃*OEt₂; BH₃*pyridine / 1,2-dichloro-ethane / 4 h / 20 °C

2: K₂CO₃ / dimethylformamide / 50 °C

3: Et₃N / CH₂Cl₂ / 0 °C

4: dimethylformamide / 20 °C

5: N₂H₄*H₂O; p-TsOH*H₂O / tetrahydrofuran / Heating

6: ethyl acetate / 20 °C

7: H₂ / 10 percent Pd/C contd. 50 percent water / ethyl acetate / 20 °C / atmospheric pressure

With borane pyridine; Trimethyl borate; boron trifluoride diethyl etherate; hydrogen; potassium carbonate; toluene-4-sulfonic acid; hydrazine hydrate; triethylamine; 10 percent Pd/C contd. 50 percent water; In tetrahydrofuran; dichloromethane; ethyl acetate; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1021/jm020239l