2-bromo-1-methoxyindane

Base Information

• Chemical Name: 2-bromo-1-methoxyindane
• CAS No.: 38135-26-1
• Molecular Formula: C₁₀H₁₁BrO
• Molecular Weight: 227.101
• Mol file: 38135-26-1.mol

Synonyms:2-bromo-1-methoxyindane

Chemical Property of 2-bromo-1-methoxyindane

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-1-methoxyindane

There total 4 articles about 2-bromo-1-methoxyindane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

1-indene (95-13-6) → 2-bromo-1-indanol (5400-80-6,78684-69-2) + 2-bromo-1-methoxyindane (38135-26-1)

Guidance literature:

With methanol; N-Bromosuccinimide; for 2h; Ambient temperature;

Reference yield: 68.0%

methanol (67-56-1) + 1-indene (95-13-6) → 2-bromo-1-indanol (5400-80-6,78684-69-2) + 2-bromo-1-methoxyindane (38135-26-1)

Guidance literature:

With N-Bromosuccinimide; for 2h; Ambient temperature;

Reference yield:

methanol (67-56-1) + peracetic acid (79-21-0) + 1-indene (95-13-6) → trans-1,2-Dibrom-indan (19598-04-0,19598-15-3,20357-79-3) + trans-2-Brom-1-methoxyindan (5927-94-6,38135-26-1,74947-78-7) + trans-2-bromo-1-indanol (79465-06-8,78684-69-2) + (1R,2R)-(-)-2-bromo-1-acetoxyindan (85354-34-3)

Guidance literature:

With dihydrogen peroxide; sodium bromide; In aq. acetate buffer; at 1 ℃; for 0.5h; pH=5.5;

DOI:10.1016/j.bbrc.2019.06.036

upstream raw materials:

methanol

peracetic acid

1-indene

Downstream raw materials:

1-(2-Bromo-4,5-dimethoxy-phenyl)-indan

1-(3,4-Dimethoxy-phenyl)-indan

1-(4-methoxyphenyl)-2,3-dihydro-1-H indene

(Z)-1-methoxy-2-(2-methoxycarbonylphenyl)ethene