1,2-Ethanediamine, N,N'-bis(1-phenylethyl)-

Base Information

• Chemical Name: 1,2-Ethanediamine, N,N'-bis(1-phenylethyl)-
• CAS No.: 6280-75-7
• Molecular Formula: C₁₈H₂₄N₂
• Molecular Weight: 268.402
• NSC Number: 6133
• DSSTox Substance ID: DTXSID10977052
• Nikkaji Number: J34.748E
• Mol file: 6280-75-7.mol

Synonyms:N,N'-Bis(1-phenylethyl)diaminoethane;1,2-Ethanediamine, N,N'-bis(1-phenylethyl)-;F 197;6280-75-7;NSC 6133;N,N'-Di(alpha-methylbenzyl)ethylenediamine;ETHYLENEDIAMINE, N,N'-BIS(alpha-METHYLBENZYL)-;N,N'-Di(.alpha.-methylbenzyl)ethylenediamine;Ethylenediamine, N,N'-bis(.alpha.-methylbenzyl)-;61484-72-8;N,N'-Bis(1-phenylethyl)ethane-1,2-diamine;WLN: 1YR&M2MYR&1;SCHEMBL3881700;DTXSID10977052;NSC6133;1, N,N'-bis(1-phenylethyl)-;LVJYSFUNASCGCN-UHFFFAOYSA-N;NSC-6133;LS-68381;N,N'-ethylene-bis-(N-1-phenylethylamine);N,N'-Bis(alpha-methylbenzyl)ethylenediamine;Ethylenediamine,N'-bis(.alpha.-methylbenzyl)-

Chemical Property of 1,2-Ethanediamine, N,N'-bis(1-phenylethyl)-

Chemical Property:

• Refractive Index: 1.6300 (estimate)
• Boiling Point: 399.58°C (rough estimate)
• Flash Point: 217.2oC
• PSA: 24.06000
• Density: 0.9274 (rough estimate)
• LogP: 4.46980
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 268.193948774
• Heavy Atom Count: 20
• Complexity: 216

Purity/Quality:

90%,98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)NCCNC(C)C2=CC=CC=C2

Technology Process of 1,2-Ethanediamine, N,N'-bis(1-phenylethyl)-

There total 11 articles about 1,2-Ethanediamine, N,N'-bis(1-phenylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(S,S)-N.N'-ethanediylidene-bis(α-methylbenzenemethylamine) → N,N'-bis[(S)-1-phenylethyl]ethane-1,2-diamine (6280-75-7,19302-22-8,19302-38-6,76740-22-2,103421-77-8)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 27h;

DOI:10.1016/j.tetlet.2016.03.036

Reference yield: 77.0%

(S)-1-phenyl-ethylamine (2627-86-3) + ethylene dibromide (106-93-4) → N,N'-bis[(S)-1-phenylethyl]ethane-1,2-diamine (6280-75-7,19302-22-8,19302-38-6,76740-22-2,103421-77-8)

Guidance literature:

With triethylamine; at 110 - 130 ℃; for 22h;

DOI:10.1016/j.tetasy.2003.09.032

Reference yield: 74.0%

(S)-1-phenyl-ethylamine (2627-86-3) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → N,N'-bis[(S)-1-phenylethyl]ethane-1,2-diamine (6280-75-7,19302-22-8,19302-38-6,76740-22-2,103421-77-8)

Guidance literature:

at 90 ℃; for 24h;

upstream raw materials:

ethylenediamine

acetophenone

D(+)-α-methylbenzylamine

(S)-1-phenyl-ethylamine

Downstream raw materials:

1,4-bis-(1-phenyl-ethyl)-piperazine

2-phenyl-1,3-(S,S)-bis-(1-phenyl-ethyl)-[1,3,2]diazaphospholidine

3-Methyl-1,5-bis-(1-phenyl-ethyl)-[1,5,3]diazaphosphepane

3-Ethyl-1,5-bis-(1-phenyl-ethyl)-[1,5,3]diazaphosphepane