3-(2-Methylpropyl)-2,5-piperazinedione

Base Information

Chemical Name:3-(2-Methylpropyl)-2,5-piperazinedione
CAS No.:5815-67-8
Molecular Formula:C₈H₁₄N₂O₂
Molecular Weight:170.211
Hs Code.:
DSSTox Substance ID:DTXSID60973726
Nikkaji Number:J46.179B
Wikidata:Q82957767
Mol file:5815-67-8.mol

Synonyms:cyclo(Gly-Leu);cyclo(glycylleucyl);cyclo(Leu-Gly);cyclo(leucylglycine);cyclo(leucylglycine), (S)-isomer

Suppliers and Price of 3-(2-Methylpropyl)-2,5-piperazinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(2-METHYLPROPYL)PIPERAZINE-2,5-DIONE 95.00%
5MG
$ 497.12

Total 3 raw suppliers

Chemical Property of 3-(2-Methylpropyl)-2,5-piperazinedione

Chemical Property:

Boiling Point:442.9°Cat760mmHg
Flash Point:207.4°C
PSA：65.18000
Density:1.047g/cm³
LogP:0.19890
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:170.105527694
Heavy Atom Count:12
Complexity:201

Purity/Quality:: 3-(2-METHYLPROPYL)PIPERAZINE-2,5-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC1C(=O)NCC(=O)N1

Technology Process of 3-(2-Methylpropyl)-2,5-piperazinedione

There total 3 articles about 3-(2-Methylpropyl)-2,5-piperazinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 51220-76-9
(N-(tert-butoxycarbonyl)-L-leucinyl)glycine ethyl ester

: 686-50-0
L-leucyl-glycine

: 5815-67-8,5845-67-0,108315-75-9
cyclo(glycyl-L-leucyl)

Guidance literature:: With water; In N,N-dimethyl-formamide; at 150 ℃; for 2.5h; enantioselective reaction; Microwave irradiation;
DOI:10.1016/j.bioorg.2010.05.002

Reference yield:

: 7325-21-5
glycyl-L-leucylglycylglycine

: 328-38-1,21675-61-6,25248-98-0,70-45-1
(R)-leucine

: 2576-67-2
[(S)-2-(2-Amino-acetylamino)-4-methyl-pentanoylamino]-acetic acid

: 131830-34-7
glycyl-D-leucylglycine

: 117760-61-9
glycyl-D-leucylglycylglycine

: 5815-67-8,5845-67-0,108315-75-9
cyclo(glycyl-L-leucyl)

: 108315-75-9
cyclo-(glycyl-D-leucyl)

Guidance literature:: In various solvent(s); at 148.5 ℃; Product distribution; Rate constant; rate of racemization was investigated during decomposition;

Reference yield:

: FA-GFLG-SN₃₈

: 623-04-1
4-aminobenzenemethanol

: C₄₉H₆₅N₁₃O₁₆

: 86639-52-3,110714-48-2,130144-34-2,113015-38-6,647852-82-2
7-ethyl-10-hydroxycamptothecin

: 5815-67-8,5845-67-0,108315-75-9
cyclo(glycyl-L-leucyl)

Guidance literature:: With ethylenediaminetetraacetic acid; cathepsin B; diothiothreitol; In aq. phosphate buffer; at 37 ℃; Enzymatic reaction;
DOI:10.1021/acsmedchemlett.0c00031