Methoxyacetaldehyde diethyl acetal

Base Information

• Chemical Name: Methoxyacetaldehyde diethyl acetal
• CAS No.: 4819-75-4
• Molecular Formula: C7H16O3
• Molecular Weight: 148.202
• European Community (EC) Number: 225-393-8
• DSSTox Substance ID: DTXSID50197454
• Nikkaji Number: J149.991B
• Wikidata: Q83070318
• Mol file: 4819-75-4.mol

Synonyms:Methoxyacetaldehyde diethyl acetal;4819-75-4;1,1-Diethoxy-2-methoxyethane;Ethane, 1,1-diethoxy-2-methoxy-;Methoxyacetaldehyde-diethylacetal;EINECS 225-393-8;METHOXYACETALDEHYDEDIETHYLACETAL;SCHEMBL2332578;PCYADPMXIILFTP-UHFFFAOYSA-;DTXSID50197454;1,1-Diethoxy-2-methoxyethane #;AKOS009156818;Methoxyacetaldehyde diethyl acetal, 97%;FT-0628303

Chemical Property of Methoxyacetaldehyde diethyl acetal

Chemical Property:

• Vapor Pressure: 5.98mmHg at 25°C
• Refractive Index: n20/D 1.399(lit.)
• Boiling Point: 144-148 °C(lit.)
• Flash Point: 95 °F
• PSA: 27.69000
• Density: 0.911 g/mL at 25 °C(lit.)
• LogP: 1.03190
• Storage Temp.: -20°C
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 148.109944368
• Heavy Atom Count: 10
• Complexity: 59.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methoxyacetaldehyde diethyl acetal 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:Flammable.
• Hazard Codes: R10:Flammable.
• Statements: 10
• Safety Statements: 16-29-33

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(COC)OCC

Technology Process of Methoxyacetaldehyde diethyl acetal

There total 2 articles about Methoxyacetaldehyde diethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium methylate (124-41-4) + Bromoacetaldehyde diethyl acetal (2032-35-1) → methoxyacetaldehyde diethyl acetal (4819-75-4)

Guidance literature:

With methanol;

Reference yield:

ethanol (64-17-5) + methoxyacetaldehyde dimethylacetal (24332-20-5) → methoxyacetaldehyde diethyl acetal (4819-75-4) + 1,1,2-triethoxyethane (4819-77-6)

Guidance literature:

With toluene-4-sulfonic acid; Heating;

DOI:10.1002/(SICI)1097-458X(199808)36:8<573::AID-OMR343>3.0.CO;2-#

Reference yield: 82.0%

methoxyacetaldehyde diethyl acetal (4819-75-4) + 3-methyl-4-phenyl-1H-pyrazol-5-amine (60419-81-0) + malononitrile (109-77-3) → 7-amino-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidine-6-carbonitrile (387361-34-4)

Guidance literature:

for 0.333333h; Reflux;

DOI:10.1134/S107042801003019X

upstream raw materials:

sodium methylate

Bromoacetaldehyde diethyl acetal

ethanol

methoxyacetaldehyde dimethylacetal

Downstream raw materials:

4,4'-dihydroxy-3,3'-(2-methoxy-ethane-1,1-diyl)-bis-chromen-2-one

DL-5-methoxymethylhydantoin

9-<2,2-bis(benzyloxymethyl)cyclopropyl>-6-chloropurine

2-(4-Bromo-2-chloro-phenyl)-2-methyl-[1,3]dioxolane