(Z)-3-(4-methoxyphenyl)-2-methylacrylic acid

Base Information

Chemical Name:(Z)-3-(4-methoxyphenyl)-2-methylacrylic acid
CAS No.:13048-81-2
Molecular Formula:C₁₁H₁₂O₃
Molecular Weight:192.214
Hs Code.:

Synonyms:(Z)-3-(4-methoxyphenyl)-2-methylacrylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-3-(4-methoxyphenyl)-2-methylacrylic acid

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Technology Process of (Z)-3-(4-methoxyphenyl)-2-methylacrylic acid

There total 27 articles about (Z)-3-(4-methoxyphenyl)-2-methylacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 52750-05-7,119870-81-4,115754-00-2
ethyl (E)-3-(4-methoxyphenyl)-2-methylpropenoate

: 13048-81-2,40527-52-4,13048-80-1
(E)-3-(4-methoxyphenyl)-2-methylacrylic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; water; for 3h; Heating;
DOI:10.1002/anie.201710601

Reference yield: 85.0%

: 30094-28-1
2-(diethylphosphono)propionic acid

: 123-11-5
4-methoxy-benzaldehyde

: 13048-81-2,40527-52-4,13048-80-1
(E)-3-(4-methoxyphenyl)-2-methylacrylic acid

Guidance literature:: 2-(diethylphosphono)propionic acid; With n-butyllithium; In tetrahydrofuran; hexane; at -60 ℃; for 1h; Inert atmosphere; Schlenk technique;

4-methoxy-benzaldehyde; In tetrahydrofuran; hexane; at -60 - 20 ℃; stereoselective reaction; Inert atmosphere; Schlenk technique;
DOI:10.1055/s-0034-1379254