[Bis(2-hydroxyethyl)ammonio]acetate

Base Information

Chemical Name:[Bis(2-hydroxyethyl)ammonio]acetate
CAS No.:150-25-4
Molecular Formula:C6H13NO4
Molecular Weight:163.174
Hs Code.:29225000
Mol file:150-25-4.mol

Synonyms:[bis(2-hydroxyethyl)ammonio]acetate;2-[bis(2-hydroxyethyl)azaniumyl]acetate;bicine buffer;CHEBI:39066

Suppliers and Price of [Bis(2-hydroxyethyl)ammonio]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Tocris
Bicine ≥99%
100G
$ 79.00

TCI Chemical
N,N-Di(2-hydroxyethyl)glycine [Good's buffer component for biological research] >99.0%(T)
500g
$ 227.00

TCI Chemical
N,N-Di(2-hydroxyethyl)glycine [Good's buffer component for biological research] >99.0%(T)
100g
$ 55.00

TCI Chemical
N,N-Di(2-hydroxyethyl)glycine [Good's buffer component for biological research] >99.0%(T)
25g
$ 21.00

SynQuest Laboratories
Bicine 99.0%
100 g
$ 23.00

SynQuest Laboratories
Bicine 99.0%
1 kg
$ 144.00

SynQuest Laboratories
Bicine 99.0%
2.5 kg
$ 272.00

Sigma-Aldrich
BICINE BioXtra, ≥99% (titration)
1kg
$ 715.00

Sigma-Aldrich
BICINE PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture
b702x
$ 681.00

Sigma-Aldrich
Bicine, ULTROL
1kg-m
$ 642.00

Total 159 raw suppliers

Chemical Property of [Bis(2-hydroxyethyl)ammonio]acetate

Chemical Property:

Appearance/Colour:White crystalline powder
Vapor Pressure:0.002-0.007Pa at 20-25℃
Melting Point:190 °C (dec.)(lit.)
Refractive Index:1.4240 (estimate)
Boiling Point:388.5 °C at 760 mmHg
PKA:8.3(at 25℃)
Flash Point:188.8 °C
PSA：81.00000
Density:1.31 g/cm³
LogP:-1.64240
Storage Temp.:2-8°C
Solubility.:H2O: 1 M at 20 °C, clear, colorless
Water Solubility.:soluble
XLogP3:-3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:163.08445790
Heavy Atom Count:11
Complexity:106

Purity/Quality:

99% ^*data from raw suppliers

Bicine ≥99% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 24/25-36-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CO)[NH+](CCO)CC(=O)[O-]
Uses To prepare stable substrate solution for the determination of guanine deaminase. The buffer is widely used with the working concentration of 3-100mM. Biological buffer and chelating agent. A zwitterionic amino acid buffer agent used for low temperature work. The use of bicine in a thin layer ion exchange chromatography method for protein resolution has been published. Bicine has been utilized in peptide and protein crystallization. A kinetic study of a quaternary transition-state analogue complex of creatine kinase used bicine in the reaction buffer. A multiphasic buffer system for SDS-PAGE of proteins and peptides that incorporates bicine has been described.

Technology Process of [Bis(2-hydroxyethyl)ammonio]acetate

There total 13 articles about [Bis(2-hydroxyethyl)ammonio]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%