{5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

Base Information

Chemical Name:{5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate
CAS No.:946570-51-0
Molecular Formula:C₂₈H₄₂O₆
Molecular Weight:474.638
Hs Code.:

Synonyms:{5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

Suppliers and Price of {5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

There total 8 articles about {5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 946570-49-6
2-(hydroxymethyl)-5-[5-methyl-3-(2-methylpropyl)hexylidene]-2-[(phenylmethoxy)methyl]-1,3-dioxolan-4-one

: 3282-30-2
pivaloyl chloride

: 946570-51-0
{5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

Guidance literature:: With triethylamine; dmap; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1021/jm0702579

Reference yield:

: 946570-43-0
1-({4-(chloromethyl)-2-[(phenylmethoxy)methyl](1,3-dioxolan-2-yl)}methoxy)-4-methoxybenzene

: 946570-51-0
{5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

Guidance literature:: Multi-step reaction with 6 steps

1.1: 80 percent / tBuOK / tetrahydrofuran / 19 h / Heating

2.1: O₃ / CH₂Cl₂; methanol / -78 °C

2.2: 71 percent / dimethyl sulfide / CH₂Cl₂; methanol / 2 h / 20 °C

3.1: lithium diisopropylamide / tetrahydrofuran; hexane / 0.5 h / -78 °C

3.2: tetrahydrofuran; hexane / 2 h / -78 °C

4.1: Et₃N; methanesulfonyl chloride / CH₂Cl₂ / 3 h / 0 - 20 °C

4.2: 37 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / CH₂Cl₂ / 20 °C

5.1: 54 percent / ammonium cerium(IV) nitrate / acetonitrile; H₂O / 0.5 h / 0 °C

6.1: 82 percent / Et₃N / dimethylaminopyridine / CH₂Cl₂ / 2 h / 0 °C

With ammonium cerium(IV) nitrate; potassium tert-butylate; ozone; methanesulfonyl chloride; triethylamine; lithium diisopropyl amide; dmap; In tetrahydrofuran; methanol; hexane; dichloromethane; water; acetonitrile;
DOI:10.1021/jm0702579

Reference yield:

: 946570-44-1
4-methoxy-1-({4-methylene-2-[(phenylmethoxy)methyl](1,3-dioxolan-2-yl)}methoxy)benzene

: 946570-51-0
{5-[5-methyl-3-(2-methylpropyl)hexylidene]-4-oxo-2-[(phenylmethoxy)methyl]-1,3-dioxolan-2-yl}methyl 2,2-dimethylpropanoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: O₃ / CH₂Cl₂; methanol / -78 °C

1.2: 71 percent / dimethyl sulfide / CH₂Cl₂; methanol / 2 h / 20 °C

2.1: lithium diisopropylamide / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: tetrahydrofuran; hexane / 2 h / -78 °C

3.1: Et₃N; methanesulfonyl chloride / CH₂Cl₂ / 3 h / 0 - 20 °C

3.2: 37 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / CH₂Cl₂ / 20 °C

4.1: 54 percent / ammonium cerium(IV) nitrate / acetonitrile; H₂O / 0.5 h / 0 °C

5.1: 82 percent / Et₃N / dimethylaminopyridine / CH₂Cl₂ / 2 h / 0 °C

With ammonium cerium(IV) nitrate; ozone; methanesulfonyl chloride; triethylamine; lithium diisopropyl amide; dmap; In tetrahydrofuran; methanol; hexane; dichloromethane; water; acetonitrile;
DOI:10.1021/jm0702579