2-Isobutyl-3-methoxypyrazine

Base Information

Chemical Name:2-Isobutyl-3-methoxypyrazine
CAS No.:24683-00-9
Molecular Formula:C9H14N2O
Molecular Weight:166.223
Hs Code.:29339900
European Community (EC) Number:246-402-1
UNII:S327O0T12O
DSSTox Substance ID:DTXSID9051907
Nikkaji Number:J126.472I
Wikipedia:3-Isobutyl-2-methoxypyrazine
Wikidata:Q15633924
Metabolomics Workbench ID:45161
ChEMBL ID:CHEMBL97355
Mol file:24683-00-9.mol

Synonyms:2-isobutyl-3-methoxypyrazine;2-methoxy-3-isobutylpyrazine;3-isobutyl-2-methoxypyrazine

Suppliers and Price of 2-Isobutyl-3-methoxypyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
2-Isobutyl-3-methoxypyrazine >97.0%(GC)(T)
1mL
$ 52.00

TCI Chemical
2-Isobutyl-3-methoxypyrazine >97.0%(GC)(T)
5mL
$ 154.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%, FG
100 g
$ 489.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%, FG
100g-k
$ 489.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%, FG
1 kg
$ 3090.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%, FG
1kg-k
$ 3090.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%, FG
500 g
$ 1810.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%, FG
500g-k
$ 1810.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%,FG
1 SAMPLE-K
$ 80.00

Sigma-Aldrich
2-Isobutyl-3-methoxypyrazine ≥99%, FG
sample-k
$ 80.00

Total 108 raw suppliers

Chemical Property of 2-Isobutyl-3-methoxypyrazine

Chemical Property:

Appearance/Colour:Clear colourless liquid
Melting Point:107oC
Refractive Index:n20/D 1.49(lit.)
Boiling Point:210.8 °C at 760 mmHg
PKA:0.80±0.10(Predicted)
Flash Point:80 °C
PSA：35.01000
Density:1g/cm³
LogP:1.68370
Storage Temp.:2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:166.110613074
Heavy Atom Count:12
Complexity:128

Purity/Quality:

99% ^*data from raw suppliers

2-Isobutyl-3-methoxypyrazine >97.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, T, F
Hazard Codes:Xi,T,F
Statements: 36/37/38-39/23/24/25-23/24/25-11
Safety Statements: 26-36-24/25-45-36/37-16-7

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC1=NC=CN=C1OC
Description 2-Isobutyl-3-methoxypyrazine has an extremely powerful odor with a reported threshold value of 2 parts per trillion in water. Diluted water solutions exhibit a characteristic odor of green bell peppers. May be synthesized by condensation of leucine amide with glyoxal, followed by methylation with CH2H2.
Uses 2-Isobutyl-3-methoxypyrazine has been employed as a model odorant molecule during an electrochemical assay for the detection of odorant molecules based on a rat odorant-binding protein (rOBP3).

Technology Process of 2-Isobutyl-3-methoxypyrazine

There total 6 articles about 2-Isobutyl-3-methoxypyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 25680-53-9
2-hydroxy-3-isobutyl-pyrazine

: 74-88-4
methyl iodide

: 24683-00-9
2-isobutyl-3-methoxypyrazine

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 20 ℃; for 48h;
DOI:10.1002/jlcr.664

Reference yield:

: D,L-leucine amide hydrochloride

: 24683-00-9
2-isobutyl-3-methoxypyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaOH / methanol; H₂O / -35 - 20 °C

2: 89 percent / NaH / tetrahydrofuran / 48 h / 20 °C

With sodium hydroxide; sodium hydride; In tetrahydrofuran; methanol; water;
DOI:10.1002/jlcr.664