2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene

Base Information

• Chemical Name: 2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene
• CAS No.: 503066-31-7
• Molecular Formula: C₁₄H₁₉N₃O₈
• Molecular Weight: 357.32
• Mol file: 503066-31-7.mol

Synonyms:2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene

Chemical Property of 2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene

There total 2 articles about 2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

benzo-10-aza-15-crown-5 (54533-83-4) → 2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene (503066-31-7)

Guidance literature:

benzo-10-aza-15-crown-5; With nitric acid; In acetic acid; at 15 - 20 ℃;

With nitric acid; In acetic acid; for 0.5h; cooling;

DOI:10.1002/1099-0690(200211)2002:22<3768::AID-EJOC3768>3.0.CO;2-R

Reference yield:

bis(o-phenylene)glycol ditosylate (54535-06-7) → 2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene (503066-31-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 16 percent / K; t-BuOH / dioxane / 40 °C

2.1: 70 percent HNO₃ / acetic acid / 15 - 20 °C

2.2: 44 percent / 90 percent HNO₃ / acetic acid / 0.5 h / cooling

With nitric acid; potassium; tert-butyl alcohol; In 1,4-dioxane; acetic acid;

DOI:10.1002/1099-0690(200211)2002:22<3768::AID-EJOC3768>3.0.CO;2-R

Reference yield: 49.0%

1,2-bis(1H-pyrrol-2-yl)ethanedione (643-78-7) + 2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene (503066-31-7) → 19,20-bis-(1H-pyrrol-2-yl)-2,5,11,14-tetraoxa-8,18,21-triaza-tricyclo[13.8.0.017,22]tricosa-1(23),15,17(22),18,20-pentaene

Guidance literature:

2,3-dinitro-6,7,10,11,12,13,15,16-octahydro-9H-5,8,14,17-tetraoxa-11-aza-benzocyclopentadecene; With hydrogen; palladium on activated charcoal; In ethanol; acetic acid; at 20 ℃; for 44h; under 2585.74 Torr;

1,2-bis(1H-pyrrol-2-yl)ethanedione; In ethanol; acetic acid; for 24h; Heating;

DOI:10.1002/1099-0690(200211)2002:22<3768::AID-EJOC3768>3.0.CO;2-R

upstream raw materials:

benzo-10-aza-15-crown-5

bis(o-phenylene)glycol ditosylate