(S)-methyl 2-chloropropanoate

Base Information Edit

Chemical Name:(S)-methyl 2-chloropropanoate
CAS No.:73246-45-4
Molecular Formula:C4H7ClO2
Molecular Weight:122.551
Hs Code.:29159000
European Community (EC) Number:412-470-8,625-379-5
UNII:I72Y13KL31
DSSTox Substance ID:DTXSID70888377
Nikkaji Number:J56.928C
Wikidata:Q27280526
ChEMBL ID:CHEMBL2074854
Mol file:73246-45-4.mol

Synonyms:73246-45-4;(S)-methyl 2-chloropropanoate;Methyl (S)-(-)-2-chloropropionate;methyl (2S)-2-chloropropanoate;Propanoic acid, 2-chloro-, methyl ester, (2S)-;Methyl (S)-2-chloropropionate;(S)-(-)-2-Chloropropionic Acid Methyl Ester;CCRIS 7389;(S)-2-Chloropropanoic acid methyl ester;Methyl 2-chloropropanoate, (S)-;(-)-Methyl (S)-2-chloropropionate;I72Y13KL31;MFCD00062941;Propanoic acid, 2-chloro-, methyl ester, (S)-;Methyl(S)-(-)-2-Chloropropionate;Methyl 2-chloropropanoate #;L(-)-2-Chloropropionate methyl ester;SCHEMBL882421;UNII-I72Y13KL31;(s)-methyl-2-chloropropionate;CHEMBL2074854;DTXSID70888377;(S)-2-Chloropropionic acid methyl;Methyl (S)-(+)-2-Chloropropionate;AKOS015848462;AKOS015904614;(-)-METHYL 2-CHLOROPROPANOATE;AM81435;CS-W011191;DS-2968;METHYL L-.ALPHA.-CHLOROPROPIONATE;(S)-2-Chloropropionic Acid methyl Ester;BP-11604;METHYL 2-CHLOROPROPANOATE, (-)-;(-)-Methyl (S)-2-chloropropionate, 98%;LS-188759;(-)-METHYL .ALPHA.-CHLOROPROPIONATE;C1634;O10227;EN300-7273899;Q27280526

Suppliers and Price of (S)-methyl 2-chloropropanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TCI Chemical
Methyl (S)-(-)-2-Chloropropionate >98.0%(GC)
5g
$ 161.00

SynQuest Laboratories
Methyl (S)-(+)-2-chloropropionate
25 g
$ 176.00

Sigma-Aldrich
(?)-Methyl (S)-2-chloropropionate 98%
5g
$ 119.00

Matrix Scientific
(S)-Methyl2-chloropropanoate >95%
25g
$ 235.00

Matrix Scientific
(S)-Methyl2-chloropropanoate >95%
5g
$ 68.00

Frontier Specialty Chemicals
(S)-(-)-2-Chloropropionicacidmethylester 98%
1g
$ 32.00

Chem-Impex
(-)-Methyl(S)-2-chloropropionate,≥96.5%(Chiralpurity)Hazmat ≥96.5%(Chiralpurity)
5G
$ 124.63

American Custom Chemicals Corporation
(S)-(-)-2 CHLOROPROPIONIC ACID METHYL ESTER 95.00%
1G
$ 640.52

AK Scientific
(S)-(-)-Methyl2-chloropropionate
1g
$ 27.00

AK Scientific
(S)-(-)-Methyl2-chloropropionate
1g
$ 20.00

Total 85 raw suppliers

Chemical Property of (S)-methyl 2-chloropropanoate Edit

Chemical Property:

Appearance/Colour:Colorless liquid
Refractive Index:n20/D 1.417(lit.)
Boiling Point:130.8 °C at 760 mmHg
Flash Point:37.6 °C
PSA：26.30000
Density:1.116 g/cm³
LogP:0.78670
Storage Temp.:-20°C
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:122.0134572
Heavy Atom Count:7
Complexity:72.1

Purity/Quality:

99.0% ^*data from raw suppliers

Methyl (S)-(-)-2-Chloropropionate >98.0%(GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 10-36-48/22
Safety Statements: 23-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)OC)Cl
Isomeric SMILES:C[C@@H](C(=O)OC)Cl
Uses (-)-Methyl α-Chloropropionate is used in the preparation of TIPTP which is a therapeutic agent for rheumatoid arthritis.

Technology Process of (S)-methyl 2-chloropropanoate

There total 15 articles about (S)-methyl 2-chloropropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 17392-83-5,2155-30-8
(R)-Methyl lactate

: 73246-45-4
methyl-(S)-2-chloropropionate

Guidance literature:: With pyridine; thionyl chloride; In N,N-dimethyl-formamide; at 20 - 55 ℃; for 5h; Temperature; Reagent/catalyst; Solvent;