<6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride

Base Information

• Chemical Name: <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride
• CAS No.: 84449-69-4
• Molecular Formula: C₄₁H₃₃NO₆S*ClH
• Molecular Weight: 704.243

Synonyms:<6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride

Chemical Property of <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride

There total 9 articles about <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-(3-methoxyphenyl-thio)-4-methoxyacetophenone (63675-73-0) → <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride (84449-69-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 69 percent / PPA / 1 h / 85 - 90 °C

2: 71 percent / pyridine hydrochloride / 6 h / 220 °C

3: 99 percent / 4-(dimethylamino)pyridine, pyridine / Ambient temperature

4: AlCl₃ / 1,2-dichloro-ethane / 1.5 h

With pyridine; dmap; aluminium trichloride; pyridine hydrochloride; In 1,2-dichloro-ethane;

DOI:10.1021/jm00374a021

Reference yield:

6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothiophene (84449-64-9) + 4-[2-(1-pyrrolidinyl)ethoxy]benzoic acid hydrochloride (63675-90-1) → <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride (84449-69-4)

Guidance literature:

aluminium trichloride;

Reference yield:

3-methoxybenzenethiol (15570-12-4) → <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride (84449-69-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 80.4 percent / KOH / ethanol; H₂O; ethyl acetate / Ambient temperature

2: 69 percent / PPA / 1 h / 85 - 90 °C

3: 71 percent / pyridine hydrochloride / 6 h / 220 °C

4: 99 percent / 4-(dimethylamino)pyridine, pyridine / Ambient temperature

5: AlCl₃ / 1,2-dichloro-ethane / 1.5 h

With pyridine; dmap; potassium hydroxide; aluminium trichloride; pyridine hydrochloride; In ethanol; water; ethyl acetate; 1,2-dichloro-ethane;

DOI:10.1021/jm00374a021

upstream raw materials:

4-[2-(1-pyrrolidinyl)ethoxy]benzoyl chloride

6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothiophene

3-methoxybenzenethiol

benzoyl chloride

Downstream raw materials:

6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-pyrrolidinoethoxy)benzoyl]benzo[b]thiophene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 84449-69-4 <6-(benzoyloxy)-2-<4-(benzoyloxy)phenyl>benzothien-3-yl><4-<2-(1-pyrrolidinyl)ethoxy>phenyl>methanone hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send