2,3-Dimethylbenzyl chloride

Base Information

• Chemical Name: 2,3-Dimethylbenzyl chloride
• CAS No.: 13651-55-3
• Molecular Formula: C9H11 Cl
• Molecular Weight: 154.639
• Hs Code.: 2903999090
• Mol file: 13651-55-3.mol

Synonyms:1-(Chloromethyl)-2,3-dimethylbenzene;2,3-Dimethylbenzyl chloride; NSC 405480

Chemical Property of 2,3-Dimethylbenzyl chloride

Chemical Property:

• Vapor Pressure: 0.119mmHg at 25°C
• Boiling Point: 227°Cat760mmHg
• Flash Point: 89.2°C
• PSA: 0.00000
• Density: 1.033g/cm³
• LogP: 3.04220
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

1-(Chloromethyl)-2,3-dimethylbenzene 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3-Dimethylbenzyl chloride

There total 12 articles about 2,3-Dimethylbenzyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.4%

(2,3-dimethylphenyl)methanol (13651-14-4) → 2,3-dimethylbenzyl chloride (13651-55-3)

Guidance literature:

With pyridine; thionyl chloride; In benzene; 1.) reflux, 1 h, 2.) room temp., 14 h;

DOI:10.1007/BF00807400

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + o-xylene (95-47-6) → 2,3-dimethylbenzyl chloride (13651-55-3) + 4-(chloromethyl)-1,2-dimethylbenzene (102-46-5)

Guidance literature:

With hydrogenchloride; at 50 - 70 ℃; Einleiten von HCl;

DOI:10.1021/ja01169a003

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + o-xylene (95-47-6) → 1,2-bis(chloromethyl)-4,5-dimethylbenzene (2362-16-5) + 2,3-dimethylbenzyl chloride (13651-55-3) + 4-(chloromethyl)-1,2-dimethylbenzene (102-46-5)

Guidance literature:

at 60 - 70 ℃;

upstream raw materials:

formaldehyd

o-xylene

(2,3-dimethylphenyl)methanol

hydrogenchloride

Downstream raw materials:

2,3-dimethylbenzaldehyde

(2,3-dimethyl-benzyl)-dimethyl-amine

2-(2,3-dimethyl-benzyl)-cyclohexanone

1,2,3-trimethylbenzene

Refernces

• 1、 Moretti, Florian,Poisson, Guillaume,Marsura, Alain. "Improved Halogenation of Methyl Aromatics and Methyl Heteroaromatics: Unexpected Reactivity of Tetrahalogeno-diphenylglycolurils". . p. 173 - 183. Retrieved 2016/05/19.
• 2、 Hu, Yu Lin,Lu, Ming,Ge, Qiang,Wang, Peng Cheng,Zhang, Sheng Bin,Lu, Ting Ting. "An inexpensive and convenient procedure for chloromethylation of aromatic hydrocarbons by phase transfer catalysis in aqueous media". experimental part. p. 97 - 102. Retrieved 2010/08/05.