2,6-Difluoro-β,β-dimethylstyrene

Base Information

• Chemical Name: 2,6-Difluoro-β,β-dimethylstyrene
• CAS No.: 135133-56-1
• Molecular Formula: C₁₀H₁₀F₂
• Molecular Weight: 168.186
• Mol file: 135133-56-1.mol

Synonyms:2,6-Difluoro-β,β-dimethylstyrene

Chemical Property of 2,6-Difluoro-β,β-dimethylstyrene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Difluoro-β,β-dimethylstyrene

There total 2 articles about 2,6-Difluoro-β,β-dimethylstyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-(2-Methyl-2-propen-1-yl)-2,6-difluorobenzene (216064-18-5) → 2,6-Difluoro-β,β-dimethylstyrene (135133-56-1)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 10h; Heating;

Reference yield:

1,3-Difluorobenzene (372-18-9) → 2,6-Difluoro-β,β-dimethylstyrene (135133-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / NaNH₂, NH₃ / 1.) -33 deg C, 0.5 h, 2.) 3 h

2: 99 percent / TsOH / benzene / 10 h / Heating

With ammonia; toluene-4-sulfonic acid; sodium amide; In benzene;

Reference yield:

2,6-Difluoro-β,β-dimethylstyrene (135133-56-1) → 2,6-difluorobenzamide (18063-03-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) O₃, 2.) NH₂OH*HCl / 1.) MeOH, 0 deg C, 2.) 0 deg C, 30 min; reflux

2: 92 percent / H₂SO₄ / 0.75 h / 125 °C

With sulfuric acid; hydroxylamine hydrochloride; ozone;

upstream raw materials:

1-(2-Methyl-2-propen-1-yl)-2,6-difluorobenzene

1,3-Difluorobenzene

Downstream raw materials:

2,6-difluoro-benzaldehyde oxime

2,6-difluorobenzoic acid

2,6-difluorobenzamide

2,6-difluorobenzoyl isocyanate

Refernces