1,1-Difluoroethane

Base Information

• Chemical Name: 1,1-Difluoroethane
• CAS No.: 75-37-6
• Deprecated CAS: 71281-71-5
• Molecular Formula: C2H4 F2
• Molecular Weight: 66.0506
• Hs Code.: 2903399090
• European Community (EC) Number: 200-866-1,687-441-8
• ICSC Number: 1729
• UN Number: 1030
• UNII: 0B1U8K2ME0
• DSSTox Substance ID: DTXSID0024050
• Nikkaji Number: J2.819C
• Wikipedia: 1,1-Difluoroethane
• Wikidata: Q161285,Q83049583
• RXCUI: 1305515
• ChEMBL ID: CHEMBL325493
• Mol file: 75-37-6.mol

Synonyms:1,1-difluoroethane;ethylidene difluoride

Chemical Property of 1,1-Difluoroethane

Chemical Property:

• Appearance/Colour: liquefied colourless gas under pressure
• Melting Point: -117 °C
• Boiling Point: -25 °C
• PSA: 0.00000
• Density: 0.907 g/cm³
• LogP: 1.27140
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 66.02810645
• Heavy Atom Count: 4
• Complexity: 11.5
• Transport DOT Label: Flammable Gas

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F
• Hazard Codes: F:Flammable
• Statements: R11:
• Safety Statements: S16:; S33:; S36:; S38:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Solvents -> Chlorofluorocarbons
• Canonical SMILES: CC(F)F
• Inhalation Risk: On loss of containment this substance can cause suffocation by lowering the oxygen content of the air in confined areas.
• Effects of Short Term Exposure: Rapid evaporation of the liquid may cause frostbite. The substance may cause effects on the cardiovascular system. This may result in cardiac disorders. Exposure at high levels could cause unconsciousness.

Technology Process of 1,1-Difluoroethane

There total 53 articles about 1,1-Difluoroethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.2%

1,1-dichloroethane (75-34-3) → 1,1-difluoroethane (75-37-6)

Guidance literature:

With hydrogen fluoride; chromium(III) oxide; at 200 ℃; for 10 - 200h; under 1500.15 Torr; Product distribution / selectivity; Molecular sieve MS-13X;

Reference yield: 95.8%

→ 1,1-difluoroethane (75-37-6) + chloroethylene (75-01-4,9002-86-2)

Guidance literature:

Reference yield: 63.0%

ethene (74-85-1) → 1,1-difluoroethane (75-37-6) + 1,2-difluoroethane (624-72-6) + 1,1,2-Trifluoroethan (430-66-0)

Guidance literature:

With xenon difluoride; silicon tetrafluoride; at 20 ℃; for 24h;

DOI:10.1002/(sici)1099-0690(199911)1999:11<3151::aid-ejoc3151>3.0.co;2-f

upstream raw materials:

1,1-dichloroethane

1,1-Dibromoethane

1-fluoroethane

Vinylidene fluoride

Downstream raw materials:

1,1-difluorotetrachloroethane

2,2,2-trifluoroethanol

1-fluoroethylene

1-Chloro-1,1-difluoroethane

Refernces

• 1、 Olah et al.. "". . p. 3387. Retrieved 1973.
• 2、 Fanfoni, Lidia,Diab, Lisa,Smejkal, Tomas,Breit, Bernhard. "Efficient synthesis of new fluorinated building blocks by means of hydroformylation". . p. 371 - 377. Retrieved 2014/08/05.
• 3、 -. "Method of producing 1,1-difluoroethane and application thereof for the production of 1,1-difluoroethylene". Page/Page column 2-3. . Retrieved 2008/06/13.