benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

Base Information

Chemical Name:benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate
CAS No.:1256776-44-9
Molecular Formula:C₂₅H₃₃N₃O₅
Molecular Weight:455.554
Hs Code.:

Synonyms:benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

Suppliers and Price of benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

There total 2 articles about benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 6401-63-4
N-benzyloxycarbonyl-L-leucyl-L-phenylalanine

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 1256776-44-9
benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

Guidance literature:: With dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/jm1009567

Reference yield:

: 10473-38-8,16679-86-0,120342-23-6,4818-00-2
N-(benzyloxycarbonyl)-L-leucyl-L-phenylalanine methyl ester

: 1256776-44-9
benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium hydroxide / methanol / 20 °C

2: dmap; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

With dmap; water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; dichloromethane;
DOI:10.1021/jm1009567

Reference yield: 80.0%

: 1256776-44-9
benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate

: 3188-13-4
ethyl chloromethyl ether

: 1256776-25-6
benzyl 1-(1-ethoxy-2-oxo-4-phenylbutan-3-ylamino)-4-methyl-1-oxopentan-2-ylcarbamate

Guidance literature:: ethyl chloromethyl ether; With magnesium; mercury dichloride; In tetrahydrofuran; Reflux; Inert atmosphere;

benzyl 1-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-ylamino)-4-methyl-1-oxopent-2-ylcarbamate; In tetrahydrofuran; at -78 - -25 ℃; for 0.75h; Inert atmosphere;
DOI:10.1021/jm1009567