4H-Pyrido[1,2-a]pyrimidin-4-one, 9-bromo-2-hydroxy-7-methyl-

Base Information

Chemical Name:4H-Pyrido[1,2-a]pyrimidin-4-one, 9-bromo-2-hydroxy-7-methyl-
CAS No.:663619-90-7
Molecular Formula:C9H7 Br N2 O2
Molecular Weight:255.071
Hs Code.:2933990090
Mol file:663619-90-7.mol

Synonyms:7-Methyl-2-hydroxy-9-bromopyrido[1,2-a]pyrimidin-4-one

Suppliers and Price of 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-bromo-2-hydroxy-7-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
9-Bromo-2-hydroxy-7-methylpyrido[1,2-a]pyrimidin-4-one 98.24%
1g
$ 225.00

ChemScene
9-Bromo-2-hydroxy-7-methylpyrido[1,2-a]pyrimidin-4-one 98.24%
250mg
$ 115.00

ChemScene
9-Bromo-2-hydroxy-7-methylpyrido[1,2-a]pyrimidin-4-one 98.24%
100mg
$ 68.00

American Custom Chemicals Corporation
9-BROMO-2-HYDROXY-7-METHYLPYRIDO[1,2-A]PYRIMIDIN-4-ONE 95.00%
5MG
$ 502.34

Alichem
9-Bromo-2-hydroxy-7-methylpyrido[1,2-a]pyrimidin-4-one
5g
$ 870.48

Alichem
9-Bromo-2-hydroxy-7-methylpyrido[1,2-a]pyrimidin-4-one
1g
$ 276.21

Total 22 raw suppliers

Chemical Property of 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-bromo-2-hydroxy-7-methyl-

Chemical Property:

Vapor Pressure:3.13E-07mmHg at 25°C
Boiling Point:377.1ºC at 760 mmHg
PKA:4.50±1.00(Predicted)
Flash Point:181.8ºC
PSA：54.60000
Density:1.79
LogP:1.47100

Purity/Quality:

97% ^*data from raw suppliers

9-Bromo-2-hydroxy-7-methylpyrido[1,2-a]pyrimidin-4-one 98.24% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-bromo-2-hydroxy-7-methyl-

There total 1 articles about 4H-Pyrido[1,2-a]pyrimidin-4-one, 9-bromo-2-hydroxy-7-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 15781-70-1
malonic acid bis-(2,4,6-trichloro-phenyl) ester

: 17282-00-7
3-bromo-5-methylpyridin-2-amine

: 663619-90-7
9-bromo-2-hydroxy-7-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

Guidance literature:: In acetone; for 2h; Reflux;
DOI:10.1016/j.bmc.2015.03.073

Reference yield:

: 663619-90-7
9-bromo-2-hydroxy-7-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

: MCA₅₁

Guidance literature:: Multi-step reaction with 2 steps

1.1: POCl₃ / 18 h / Heating

1.2: 38.8 percent / ethanol / 1 h / Heating

2.1: 12.6 percent / potassium tert-butoxide / PdCl₂(dppf) / tetrahydrofuran / 24 h / Heating

With potassium tert-butylate; trichlorophosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran;
DOI:10.1016/j.bmc.2004.06.022

Reference yield:

: 663619-90-7
9-bromo-2-hydroxy-7-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

: TGX₁₂₆

Guidance literature:: Multi-step reaction with 2 steps

1.1: POCl₃ / 18 h / Heating

1.2: 38.8 percent / ethanol / 1 h / Heating

2.1: 61 percent / potassium tert-butoxide / PdCl₂(dppf) / tetrahydrofuran / 24 h / Heating

With potassium tert-butylate; trichlorophosphate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran;
DOI:10.1016/j.bmc.2004.06.022