4-Methoxynicotinaldehyde

Base Information

Chemical Name:4-Methoxynicotinaldehyde
CAS No.:82257-15-6
Molecular Formula:C7H7NO2
Molecular Weight:137.138
Hs Code.:2933399090
European Community (EC) Number:636-011-8
DSSTox Substance ID:DTXSID40462547
Nikkaji Number:J273.988G
Wikidata:Q72485784
Mol file:82257-15-6.mol

Synonyms:82257-15-6;4-methoxynicotinaldehyde;4-Methoxypyridine-3-carboxaldehyde;4-methoxypyridine-3-carbaldehyde;3-Formyl-4-methoxypyridine;4-Methoxy-3-pyridinecarboxaldehyde;4-Methoxy-pyridine-3-carbaldehyde;4-Methoxy-3-pyridine carboxaldehyde;4-methoxy-pyridine-3-carbaldehye;4-methoxy-3-formoylpyridine;Nicotinamidase Inhibitor, 22;SCHEMBL1605930;BDBM92855;DTXSID40462547;QWUFIMUCFQUBOT-UHFFFAOYSA-N;AMY15253;CS-D0961;pyridine-4-methoxy-3-carboxaldehyde;4-Methoxynicotinaldehyde, AldrichCPR;MFCD04112505;AKOS005264537;AB17569;AC-14827;DS-11177;BB 0260211;FT-0646580;EN300-112298;J-512573

Suppliers and Price of 4-Methoxynicotinaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methoxypyridine-3-carboxaldehyde
100mg
$ 120.00

SynQuest Laboratories
4-Methoxynicotinaldehyde
1 g
$ 788.00

Medical Isotopes, Inc.
4-Methoxypyridine-3-carboxaldehyde
250 mg
$ 650.00

Medical Isotopes, Inc.
4-Methoxypyridine-3-carboxaldehyde
100 mg
$ 610.00

Matrix Scientific
4-Methoxynicotinaldehyde
1g
$ 250.00

Matrix Scientific
4-Methoxynicotinaldehyde
2.500g
$ 375.00

Matrix Scientific
4-Methoxynicotinaldehyde
500mg
$ 150.00

J&W Pharmlab
4-Methoxy-pyridine-3-carbaldehyde 97%
1g
$ 98.00

J&W Pharmlab
4-Methoxy-pyridine-3-carbaldehyde 97%
5g
$ 398.00

Crysdot
4-Methoxypyridine-3-carboxaldehyde 95%
5g
$ 465.00

Total 59 raw suppliers

Chemical Property of 4-Methoxynicotinaldehyde

Chemical Property:

Appearance/Colour:light yellow solid
Vapor Pressure:0.011mmHg at 25°C
Melting Point:63-67 °C
Refractive Index:1.551
Boiling Point:262.893 °C at 760 mmHg
PKA:4.75±0.18(Predicted)
Flash Point:112.794 °C
PSA：39.19000
Density:1.159 g/cm³
LogP:0.90270
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:137.047678466
Heavy Atom Count:10
Complexity:116

Purity/Quality:

99% ^*data from raw suppliers

4-Methoxypyridine-3-carboxaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-37/38-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=NC=C1)C=O
Uses 4-Methoxypyridine-3-carboxaldehyde, is an intermediate for the synthesis of 4-Hydroxy-3-pyridinecarboxylic Acid (H952780). It can also be used for the preparation of 7,8-dimethylquinolines derivatives as potential antimicrobial and antifungal agents.

Technology Process of 4-Methoxynicotinaldehyde

There total 8 articles about 4-Methoxynicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 124-41-4
sodium methylate

: 114077-82-6
4-chloronicotinaldehyde

: 82257-15-6
4-methoxynicotinaldehyde

Guidance literature:: In methanol; for 0.5h; Heating;

Reference yield: 85.0%

: 620-08-6,1232006-56-2
4-methoxypyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 82257-15-6
4-methoxynicotinaldehyde

Guidance literature:: With 2,4,6-trimethylphenyl bromide; tert.-butyl lithium;
DOI:10.1016/j.tetlet.2005.10.119

Reference yield: 79.0%

: 82257-09-8
bromo-3 methoxy-4 pyridine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 82257-15-6
4-methoxynicotinaldehyde

Guidance literature:: bromo-3 methoxy-4 pyridine; With n-butyllithium; In tetrahydrofuran; at -78 ℃;

N,N-dimethyl-formamide; In tetrahydrofuran; Further stages.;
DOI:10.1002/1099-0690(200207)2002:13<2126::AID-EJOC2126>3.0.CO;2-A