4-Carboxy-2-chlorophenylboronic acid

Base Information

Chemical Name:4-Carboxy-2-chlorophenylboronic acid
CAS No.:851335-09-6
Molecular Formula:C7H6 B Cl O4
Molecular Weight:200.386
Hs Code.:2931900090
European Community (EC) Number:834-904-9
DSSTox Substance ID:DTXSID10590366
Wikidata:Q82484077
Mol file:851335-09-6.mol

Synonyms:AB-0024;AB0024;GS-6624;simtuzumab

Suppliers and Price of 4-Carboxy-2-chlorophenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Carboxy-2-chlorophenylboronicacid
1g
$ 75.00

TRC
4-Carboxy-2-chlorophenylboronicacid
100mg
$ 45.00

TCI Chemical
4-Carboxy-2-chlorophenylboronic Acid (contains varying amounts of Anhydride)
1g
$ 66.00

SynQuest Laboratories
4-Carboxy-2-chlorobenzeneboronic acid 97%
100 g
$ 1156.00

SynQuest Laboratories
4-Carboxy-2-chlorobenzeneboronic acid 97%
25 g
$ 391.00

SynQuest Laboratories
4-Carboxy-2-chlorobenzeneboronic acid 97%
5 g
$ 151.00

Sigma-Aldrich
2-Chloro-4-carboxyphenylboronic acid Aldrich
1g
$ 57.00

Matrix Scientific
4-Carboxy-2-chlorophenylboronic acid
5g
$ 78.00

Matrix Scientific
4-Carboxy-2-chlorophenylboronic acid
25g
$ 260.00

Crysdot
4-Carboxy-2-chlorophenylboronicacid 97%
100g
$ 543.00

Total 61 raw suppliers

Chemical Property of 4-Carboxy-2-chlorophenylboronic acid

Chemical Property:

Vapor Pressure:3.79E-08mmHg at 25°C
Melting Point:208-210 ºC
Boiling Point:429.7 ºC at 760 mmHg
PKA:3.71±0.10(Predicted)
Flash Point:213.7 ºC
PSA：77.76000
Density:1.55 g/cm³
LogP:-0.28200
Storage Temp.:Keep Cold
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:200.0047665
Heavy Atom Count:13
Complexity:199

Purity/Quality:

99% ^*data from raw suppliers

4-Carboxy-2-chlorophenylboronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C=C(C=C1)C(=O)O)Cl)(O)O
Recent ClinicalTrials:A Study to Evaluate the Safety and Efficacy of GS-6624 (Formerly AB0024) in Patients With Idiopathic Pulmonary Fibrosis
Recent EU Clinical Trials:A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety and Efficacy of GS-6624, a Monoclonal Antibody Against Lysyl Oxidase-Like 2 (LOXL2), in Subjects with Advanced Liver Fibrosis but not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH)
Uses suzuki reaction Reactant in the synthesis and characterization1, 3, 4-oxadiazole.

Technology Process of 4-Carboxy-2-chlorophenylboronic acid

There total 1 articles about 4-Carboxy-2-chlorophenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 851335-09-6
2-chloro-4-carboxybenzeneboronic acid

Guidance literature:

Reference yield: 78.0%

: 851335-09-6
2-chloro-4-carboxybenzeneboronic acid

: 6-bromo-3-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-3H-[1,2,3]triazolo[4,5-c]pyridine

: 3-chloro-4-{3-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-3H-[1,2,3]triazolo[4,5-c]pyridin-6-yl}benzoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In ethanol; for 5h; Heating;
DOI:10.1016/j.bmc.2017.06.014

Reference yield: 70.76%

: 3140-92-9
2,4-dibromothiophene

: 851335-09-6
2-chloro-4-carboxybenzeneboronic acid

: 4-(4-bromothiophen-2-yl)-3-chlorobenzoic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; N,N-dimethyl-formamide; at 100 ℃; for 16h; Inert atmosphere; Sealed tube;