(S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

Base Information

Chemical Name:(S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate
CAS No.:1423720-72-2
Molecular Formula:C₁₈H₂₇NO₆
Molecular Weight:353.415
Hs Code.:

Synonyms:(S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

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Chemical Property of (S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

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Technology Process of (S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

There total 2 articles about (S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1423720-71-1
(S)-tert-butyl 4-(3,5-diiodo-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

: 1423720-72-2
(S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

: 1426447-06-4
C₁₈H₂₇NO₅

: 1426447-07-5
C₁₈H₂₆INO₅

Guidance literature:: (S)-tert-butyl 4-(3,5-diiodo-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 2h; Inert atmosphere;

With Trimethyl borate; In diethyl ether; hexane; at -78 - 35 ℃; Inert atmosphere;

With dihydrogen peroxide; acetic acid; In diethyl ether; hexane; at 0 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2013.02.079

Reference yield: 35.0%

: 1426447-08-6
(S)-tert-butyl 4-(3,5-dibromo-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

: 1423720-72-2
(S)-tert-butyl 4-(3,5-dihydroxy-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate

: 1426447-06-4
C₁₈H₂₇NO₅

: 1426447-09-7
C₁₈H₂₆BrNO₅

Guidance literature:: (S)-tert-butyl 4-(3,5-dibromo-4-methoxybenzyl)-2,2-dimethyloxazolidine-3-carboxylate; With n-butyllithium;

With Trimethyl borate;

With dihydrogen peroxide; acetic acid;
DOI:10.1016/j.tet.2013.02.079