Cholest-5-en-3-ol (3beta)-, (9Z)-9-octadecenyl carbonate

Base Information

• Chemical Name: Cholest-5-en-3-ol (3beta)-, (9Z)-9-octadecenyl carbonate
• CAS No.: 17110-51-9
• Molecular Formula: C46H80O3
• Molecular Weight: 681.139
• Hs Code.: 29209090
• European Community (EC) Number: 241-179-7
• Wikipedia: Cholesteryl_oleyl_carbonate
• Mol file: 17110-51-9.mol

Synonyms:Cholesteryl oleyl carbonate;17110-51-9;C46H80O3;C46-H80-O3;Cholesterol, 9-octadecenyl carbonate, (Z)-;Cholest-5-en-3-ol (3.beta.)-, (9Z)-9-octadecenyl carbonate;SCHEMBL246735

Chemical Property of Cholest-5-en-3-ol (3beta)-, (9Z)-9-octadecenyl carbonate

Chemical Property:

• Appearance/Colour: white to pale yellow waxy liquid
• Vapor Pressure: 3.65E-20mmHg at 25°C
• Melting Point: 20 °C
• Refractive Index: 1.51
• Boiling Point: 712.8 °C at 760 mmHg
• Flash Point: 152.3 °C
• PSA: 35.53000
• Density: 0.97 g/cm³
• LogP: 14.58710
• XLogP3: 17.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 24
• Exact Mass: 680.61074641
• Heavy Atom Count: 49
• Complexity: 1010

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cholesteryl oleyl carbonate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Biological Agents -> Cholesterol and Derivatives
• Canonical SMILES: CCCCCCCCC=CCCCCCCCCOC(=O)OC1CCC2(C3CCC4(C(C3CC=C2C1)CCC4C(C)CCCC(C)C)C)C
• Isomeric SMILES: CCCCCCCC/C=C/CCCCCCCCOC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4[C@H](C)CCCC(C)C)C)C
• Uses: COC can be incorporated in the polyethylene glycol(PEG)-polyurethane(PU) matrix that exhibits lower thrombogenicity and an improved haemocompatibility which can used as a biomaterial in biomedical applications. It may also be self-assembled with cadmium selenide(CdSe) quantum dots(QDs) for the fabrication of novel multifunctional switchable devices.

Technology Process of Cholest-5-en-3-ol (3beta)-, (9Z)-9-octadecenyl carbonate

There total 3 articles about Cholest-5-en-3-ol (3beta)-, (9Z)-9-octadecenyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oleoyl alcohol (143-28-2,593-47-5,84286-21-5) + 3β-ethoxycarbonyloxycholest-5-ene (23836-43-3) → cholesteric-oleyl-carbonate (17110-51-9,76202-42-1)

Guidance literature:

With Lipozyme IM; at 80 ℃; for 48h; under 15.0012 Torr;

DOI:10.1021/jf0107407

Reference yield:

cholesterol (57-88-5) → cholesteric-oleyl-carbonate (17110-51-9,76202-42-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Lipozyme IM; molecular sieve 4 Angstroem / 48 h / 60 °C / 300.02 Torr

2: Lipozyme IM / 48 h / 80 °C / 15 Torr

With Lipozyme IM; 4 A molecular sieve;

DOI:10.1021/jf0107407

Reference yield:

→ Cholesteryl-oleyl-carbonat (17110-51-9,76202-42-1)

Guidance literature:

Cholesteryl-chloroformat, Oleylalkohol, Py./Bzl.;

upstream raw materials:

oleoyl alcohol

3β-ethoxycarbonyloxycholest-5-ene

cholesterol

Refernces