trans-Diamminediiodoplatinum(II)

Base Information

• Chemical Name: trans-Diamminediiodoplatinum(II)
• CAS No.: 15978-93-5
• Deprecated CAS: 23555-38-6
• Molecular Formula: H₆I₂N₂Pt
• Molecular Weight: 482.95
• DSSTox Substance ID: DTXSID40936172
• Mol file: 15978-93-5.mol

Synonyms:cis-diammine-diiodoplatin;CPJ2;diammine-diiodoplatin;diamminediiodoplatinum

Chemical Property of trans-Diamminediiodoplatinum(II)

Chemical Property:

• Vapor Pressure: 5990mmHg at 25°C
• PSA: 52.04000
• LogP: 1.98830
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 482.82684
• Heavy Atom Count: 5
• Complexity: 0

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: N.N.[I-].[I-].[Pt+2]
• Uses: cis-Diiododiammineplatinum(II) is a diiodo analog of cis-platin. cis-Diiododiammineplatinum(II) exhibits similar DNA binding modes as cis-platin by greater DNA reactivities towards tumor cell lines.

Technology Process of trans-Diamminediiodoplatinum(II)

There total 17 articles about trans-Diamminediiodoplatinum(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.1%

ammonium hydroxide (1336-21-6) + potassium tetrachloroplatinate(II) (10025-99-7) + potassium iodide (7681-11-0) → cis-diamminediiodoplatinum (II) (13841-96-8,15978-93-5,15978-94-6)

Guidance literature:

potassium tetrachloroplatinate(II); potassium iodide; In water; at 40 - 60 ℃; Darkness;

ammonium hydroxide; In water; Darkness;

Reference yield: 91.0%

potassium tetrachloroplatinate + ammonium hydroxide (1336-21-6) + potassium iodide (7681-11-0) → cis-diamminediiodidoplatinum(II) (13841-96-8,15978-93-5,15978-94-6)

Guidance literature:

potassium tetrachloroplatinate; potassium iodide; In water; at 36 - 40 ℃; for 0.166667h;

ammonium hydroxide; In water;

DOI:10.1021/ic402611m

Reference yield: 80.0%

tetrammineplatinum(II) iodide (14708-49-7) → trans-diiododiammineplatinum(II) (15978-93-5,13841-96-8,15978-94-6)

Guidance literature:

With water; In water; passing of water-steam through a (Pt(NH3)4)I2-soln. for 2-3 h; cooling down;; washing crystal-powder with a small amount of hot H2O;;

upstream raw materials:

potassium iodide

transplatin

{Pta₂aesCl}Cl

tetrammineplatinum(II) iodide

Downstream raw materials:

trans-dinitrato-diammine-platinum(II)

trans-bis(phenylamino)diiodoplatinum(II)

trans-diamminetetrachloroplatinum(IV)

tetrammineplatinum(II) iodide