1R,2R-1,2-Di(4'-methoxyphenyl)-1,2-diaminoethan

Base Information

• Chemical Name: 1R,2R-1,2-Di(4'-methoxyphenyl)-1,2-diaminoethan
• CAS No.: 58520-04-0
• Molecular Formula: C16H20 N2 O2
• Molecular Weight: 272.347
• Mol file: 58520-04-0.mol

Synonyms:1,2-Ethanediamine,1,2-bis(4-methoxyphenyl)-, [S-(R*,R*)]- (9CI);(1S,2S)-1,2-Bis(4-methoxyphenyl)-1,2-ethanediamine

Chemical Property of 1R,2R-1,2-Di(4'-methoxyphenyl)-1,2-diaminoethan

Chemical Property:

• Melting Point: 89-91°C
• Boiling Point: 438.2°Cat760mmHg
• PKA: 10.21±0.10(Predicted)
• Flash Point: 231.9°C
• PSA: 70.50000
• Density: 1.135g/cm³
• LogP: 3.80420
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Sensitive.: Air Sensitive

Purity/Quality:

99% ^*data from raw suppliers

(1S,2S)-1,2-Bis(4-methoxyphenyl)ethylenediamine dihydrochloride 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1R,2R-1,2-Di(4'-methoxyphenyl)-1,2-diaminoethan

There total 4 articles about 1R,2R-1,2-Di(4'-methoxyphenyl)-1,2-diaminoethan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C30H28N2O4 → (1S,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine (58520-04-0,117106-36-2)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 3h;

Reference yield:

d,l-1,2-diamino-1,2-bis(4-methoxyphenyl)ethane (117106-36-2) → (1S,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine (58520-04-0,117106-36-2)

Guidance literature:

DOI:10.1016/0957-4166(94)00336-A

Reference yield:

d,l-1,2-diamino-1,2-bis(4-methoxyphenyl)ethane (117106-36-2) → (1R,2R)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine (58520-03-9,117106-36-2) + (1S,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine (58520-04-0,117106-36-2)

Guidance literature:

With ditoluoyltartaric acid; In methanol; Purification / work up; Resolution of racemate;

upstream raw materials:

d,l-1,2-diamino-1,2-bis(4-methoxyphenyl)ethane

4-methoxy-benzaldehyde

Downstream raw materials:

(S,S)-1,2-Bis(4-hydroxyphenyl)-1,2-ethanediamine

C₂₃H₂₂N₂O₂

C₃₈H₄₂N₄O₈S₂

C₅₇H₅₄N₆O₆

Refernces

• 1、 -. "TRANSITION METAL COMPLEXES FOR ENANTIOSELECTIVE CATALYSIS OF CARBON-CARBON, CARBON-HETEROATOM, AND CARBON-HYDROGEN BOND FORMING REACTIONS". . . Retrieved 2014/02/16.
• 2、 Corey, E. J.,Lee, Duck-Hyung,Sarshar, Sepehr. "Convenient Routes to Symmetrical Benzils and Chiral 1,2-Diaryl-1,2-diaminoethanes, Useful Controllers and Probes for Enantioselective Synthesis". . p. 3 - 6. Retrieved 2007/10/02.