(1R,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine

Base Information Edit

Chemical Name:(1R,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine
CAS No.:117106-36-2
Molecular Formula:C₁₆H₂₀N₂O₂
Molecular Weight:272.347
Hs Code.:
European Community (EC) Number:622-829-2,809-397-2
Mol file:117106-36-2.mol

Synonyms:58520-45-9;(1R,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine;meso-1,2-Bis(4-methoxyphenyl)ethylenediamine;117106-36-2;1,2-Ethanediamine, 1,2-bis(4-methoxyphenyl)-, (1R,2S)-rel-;starbld0005408;SCHEMBL591062;58520-04-0;meso-1,2-Bis(4-methoxyphenyl)ethane-1,2-diamine;rel-(1R,2S)-1,2-Bis(4-methoxyphenyl)ethane-1,2-diamine;1,2-Ethanediamine,1,2-bis(4-methoxyphenyl)-,(1R,2S)-rel-;meso-1,2-Bis(4-methoxyphenyl)ethylenediamine, for HPLC derivatization, >=98.0% (NT)

Suppliers and Price of (1R,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1R,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine Edit

Chemical Property:

Vapor Pressure:7.01E-08mmHg at 25°C
Melting Point:150-155 °C(lit.)
Refractive Index:1.588
Boiling Point:438.2°C at 760 mmHg
Flash Point:231.9°C
PSA：70.50000
Density:1.135g/cm³
LogP:3.80420
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:272.152477885
Heavy Atom Count:20
Complexity:244

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(C(C2=CC=C(C=C2)OC)N)N
Isomeric SMILES:COC1=CC=C(C=C1)[C@H]([C@H](C2=CC=C(C=C2)OC)N)N

Technology Process of (1R,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine

There total 53 articles about (1R,2S)-1,2-bis(4-methoxyphenyl)ethane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 162407-08-1
2,3-Bis-(4-methoxy-phenyl)-1,4-diaza-spiro[4.5]deca-1,3-diene

: 117106-36-2
d,l-1,2-diamino-1,2-bis(4-methoxyphenyl)ethane

Guidance literature:: 2,3-Bis-(4-methoxy-phenyl)-1,4-diaza-spiro[4.5]deca-1,3-diene; With ammonia; lithium; In tetrahydrofuran; at -78 - -60 ℃; for 0.5 - 1h;

With ethanol; In tetrahydrofuran; for 0.5 - 1h;

With hydrogenchloride; potassium hydroxide; ammonium chloride; more than 3 stages;

Reference yield: 62.0%

: 123-11-5
4-methoxy-benzaldehyde

: 51208-43-6,117106-36-2
meso-1,2-bis-(p-methoxyphenyl)-ethylenediamine

Guidance literature:: With tris(bipyridine)ruthenium(II) dichloride hexahydrate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; ammonia; scandium tris(trifluoromethanesulfonate); In methanol; acetonitrile; at 0 - 25 ℃; for 15h; chemoselective reaction; Sealed tube; Inert atmosphere; Irradiation;
DOI:10.1021/acs.orglett.8b01637