6-Chloro-2-iodopurine

Base Information

Chemical Name:6-Chloro-2-iodopurine
CAS No.:18552-90-4
Molecular Formula:C5H2ClIN4
Molecular Weight:280.455
Hs Code.:2933990090
European Community (EC) Number:803-076-0
DSSTox Substance ID:DTXSID30463583
Nikkaji Number:J1.614.349I
Wikidata:Q72483486
Mol file:18552-90-4.mol

Synonyms:6-chloro-2-iodopurine

Suppliers and Price of 6-Chloro-2-iodopurine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-2-iodopurine
2.5g
$ 770.00

TRC
6-Chloro-2-iodopurine
100mg
$ 55.00

Sigma-Aldrich
6-Chloro-2-iodopurine 97%
250mg
$ 164.00

Matrix Scientific
6-Chloro-2-iodopurine 95+%
250mg
$ 352.00

Crysdot
6-Chloro-2-iodopurine 95+%
1g
$ 315.00

Chemenu
6-chloro-2-iodo-7H-purine 95%
1g
$ 355.00

Chemenu
6-chloro-2-iodo-7H-purine 95%
5g
$ 978.00

Biosynth Carbosynth
6-Chloro-2-iodopurine
250 mg
$ 200.00

American Custom Chemicals Corporation
6-CHLORO-2-IODOPURINE 95.00%
5G
$ 3106.95

American Custom Chemicals Corporation
6-CHLORO-2-IODOPURINE 95.00%
1G
$ 1676.85

Total 39 raw suppliers

Chemical Property of 6-Chloro-2-iodopurine

Chemical Property:

Melting Point:198-203°C
Boiling Point:582.2 °C at 760 mmHg
PKA:5.55±0.20(Predicted)
Flash Point:305.9 °C
PSA：54.46000
Density:2.426 g/cm³
LogP:1.61090
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:279.90127
Heavy Atom Count:11
Complexity:157

Purity/Quality:

99%, ^*data from raw suppliers

6-Chloro-2-iodopurine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC2=C(N1)C(=NC(=N2)I)Cl
Uses 6-Chloro-2-iodopurine is used as a reagent in the synthesis of MRS 2500 Tetraammonium Salt (M750200); a highly potent and selective antagonist of the platelet P2Y1 receptor that inhibits ADP-induced aggregation of human platelets. 6-Chloro-2-iodopurine is also used in the preparation of methanocarba disubstituted adenine nucleosides as highly potent and selective A3 adenosine receptor agonists.

Technology Process of 6-Chloro-2-iodopurine

There total 13 articles about 6-Chloro-2-iodopurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 403620-89-3
6-chloro-2-iodo-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

: 18552-90-4
6-chloro-2-iodo-(9H)-purine

Guidance literature:: With copper dichloride; In ethanol; at 85 ℃; for 5h;
DOI:10.1039/b312629c

Reference yield: 76.0%

: 470483-92-2
9-acetyl-2-amino-6-chloro-9H-purine

: 18552-90-4
6-chloro-2-iodo-(9H)-purine

Guidance literature:: With iodine; isopentyl nitrite; In tetrahydrofuran; at 50 - 60 ℃;

Reference yield: 73.0%

: 10310-21-1
2-amino-6-chloropurine

: 18552-90-4
2-iodo-6-chloropurine

Guidance literature:: With copper(l) iodide; diiodomethane; isopentyl nitrite; In N,N-dimethyl-formamide; at 120 ℃; for 2h; Microwave irradiation;
DOI:10.1016/j.tet.2009.08.057