2-deuteriochlorobenzene

Base Information

• Chemical Name: 2-deuteriochlorobenzene
• CAS No.: 19256-46-3
• Molecular Formula: C₆H₅Cl
• Molecular Weight: 113.551
• Mol file: 19256-46-3.mol

Synonyms:2-deuteriochlorobenzene

Chemical Property of 2-deuteriochlorobenzene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-deuteriochlorobenzene

There total 4 articles about 2-deuteriochlorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-bromo-1-chlorobenzene (694-80-4) → 2-deuteriochlorobenzene (19256-46-3)

Guidance literature:

With tetradeuterioacetic acid; magnesium; In diethyl ether; 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1002/anie.201501992

Reference yield:

2-iodochlorobenzene (615-41-8) → 2-deuteriochlorobenzene (19256-46-3)

Guidance literature:

With diethyl ether; magnesium; anschliessendes Behandeln mit O-Deuterio-essigsaeure;

DOI:10.1021/ja01584a024

Reference yield:

d(4)-methanol (811-98-3) + C14H11BF5N + chlorobenzene (108-90-7) → 1-deutero-2,3,4,5,6-pentafluorobenzene (1423-07-0) + 1-chloro-3-deuterio-benzene (19256-47-4) + 1-chloro-4-deuterio-benzene (13122-34-4) + 2-deuteriochlorobenzene (19256-46-3) + C10H10(2)H6BNO2

Guidance literature:

C₁₄H₁₁BF₅N; chlorobenzene; In neat (no solvent); at 80 ℃; for 24h; Schlenk technique; Inert atmosphere;

d⁽⁴⁾-methanol; In neat (no solvent); at 120 ℃; for 0.166667h; Schlenk technique; Inert atmosphere;

DOI:10.1021/jacs.6b00819

upstream raw materials:

2-iodochlorobenzene

2-bromo-1-chlorobenzene

d⁽⁴⁾-methanol

chlorobenzene

Downstream raw materials:

o-deuterioiodobenzene

2-(tert-butyl)-bis(2-deuteriophenyl)silyl-3-methoxyphenyl trifluoromethanesulfonate

1-bromo-2-deuterobenzene