L-tyrosyl-L-alanine

Base Information

• Chemical Name: L-tyrosyl-L-alanine
• CAS No.: 730-08-5
• Molecular Formula: C12H16N2O4
• Molecular Weight: 252.27
• Hs Code.: 2924299090
• Mol file: 730-08-5.mol

Synonyms:L-tyrosyl-L-alanine

Chemical Property of L-tyrosyl-L-alanine

Chemical Property:

• Vapor Pressure: 3.42E-14mmHg at 25°C
• Melting Point: 230℃ (Decomposition)
• Refractive Index: 1.591
• Boiling Point: 577.8 °C at 760 mmHg
• Flash Point: 303.3 °C
• PSA: 112.65000
• Density: 1.315 g/cm³
• LogP: 0.94250
• Storage Temp.: −20°C
• XLogP3: -2.4
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 252.11100700
• Heavy Atom Count: 18
• Complexity: 295

Purity/Quality:

98%Min ^*data from raw suppliers

Tyr-Ala ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)[O-])NC(=O)C(CC1=CC=C(C=C1)O)[NH3+]
• Isomeric SMILES: C[C@@H](C(=O)[O-])NC(=O)[C@H](CC1=CC=C(C=C1)O)[NH3+]

Technology Process of L-tyrosyl-L-alanine

There total 2 articles about L-tyrosyl-L-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(N-benzyloxycarbonyl-L-tyrosyl)-Ξ-alanine (23018-09-9) → N-L-tyrosyl-Ξ-alanine (730-08-5,67035-21-6,76572-16-2,122774-42-9)

Guidance literature:

With methanol; palladium; acetic acid; Hydrogenolyse;

Reference yield:

→ L-tyrosyl-L-alanine (730-08-5)

Guidance literature:

DOI:10.1016/S0040-4020(01)90729-X

Reference yield: 71.0%

methanol (67-56-1) + L-tyrosyl-L-alanine (730-08-5) → benzyl methyl ether (538-86-3) + L-alanin (56-41-7,25191-17-7,18875-37-1)

Guidance literature:

With potassium hydroxide; [bis(acetoxy)iodo]benzene; at 0 - 5 ℃; for 1.5h;

DOI:10.1039/c39850000974

upstream raw materials:

N-(N-benzyloxycarbonyl-L-tyrosyl)-Ξ-alanine

Downstream raw materials:

benzyl methyl ether

L-alanin