N,N-diisopropylethylamine borane

Base Information

• Chemical Name: N,N-diisopropylethylamine borane
• CAS No.: 88996-23-0
• Molecular Formula: C8H22 B N
• Molecular Weight: 143.08
• European Community (EC) Number: 628-386-1
• DSSTox Substance ID: DTXSID30472736
• Mol file: 88996-23-0.mol

Synonyms:88996-23-0;N,N-diisopropylethylamine borane;SCHEMBL319537;borane-n,n-diisopropylethylamine;SCHEMBL3978500;DTXSID30472736;BYKCUMSOQIPHSR-UHFFFAOYSA-N;DWXQHSSGDGWIMP-UHFFFAOYSA-N;borane n,n-diisopropyl ethyl amine;AMY14922;FT-0642108

Chemical Property of N,N-diisopropylethylamine borane

Chemical Property:

• Melting Point: 15-17 °C(lit.)
• Refractive Index: n20/D 1.46(lit.)
• Flash Point: 40 ºC
• PSA: 3.24000
• Density: 0.822
• LogP: 0.94120
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 140.1610548
• Heavy Atom Count: 10
• Complexity: 59

Purity/Quality:

98%,99%, ^*data from raw suppliers

Borane N,N-diisopropylethylamine complex ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 10-34
• Safety Statements: 16-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [B].CCN(C(C)C)C(C)C
• Uses: Reactant for:Preparation of modifiable bidentate systems via nitrogen-carbon rearrangementPreparation of bioactive boranophosphonic acidsPreparation of precursors for synthesis of boronated oligonucleotide sequencesSynthesis of dithymidine boranophosphate via the oxathiaphospholane approachPreparation of adenosine boranothiotriphosphate ribonucleoside and thymidine boranothiotriphosphate deoxyribonucleosidePreparation of borane-amine complexes

Technology Process of N,N-diisopropylethylamine borane

There total 4 articles about N,N-diisopropylethylamine borane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

Trimethyl borate (121-43-7,63156-11-6) + N-ethyl-N,N-diisopropylamine (7087-68-5) → borane-N,N-diisopropylethylamine complex (88996-23-0)

Guidance literature:

Trimethyl borate; N-ethyl-N,N-diisopropylamine; With lithium hydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

With aluminum (III) chloride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol302421t

Reference yield: 61.0%

sodium tetrahydroborate (16940-66-2) + N-ethyl-N,N-diisopropylamine (7087-68-5) → borane-N,N-diisopropylethylamine complex (88996-23-0)

Guidance literature:

With carbon dioxide; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1039/d1dt03495b

Reference yield:

ammonium sulfate (24270-55-1,7783-20-2,82168-61-4,13775-30-9) + sodium tetrahydroborate (16940-66-2) + ammonia (7664-41-7) + N-ethyl-N,N-diisopropylamine (7087-68-5) → borane-ammonia complex (10043-11-5) + borane-N,N-diisopropylethylamine complex (88996-23-0) + borazine (6569-51-3)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 24h; under 760.051 Torr; Time; Temperature;

DOI:10.1039/c6dt02925f

upstream raw materials:

Trimethyl borate

N-ethyl-N,N-diisopropylamine

diborane

ammonium sulfate