2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate

Base Information

• Chemical Name: 2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate
• CAS No.: 92502-98-2
• Molecular Formula: C₇H₈NO₃S*Na
• Molecular Weight: 209.201
• Mol file: 92502-98-2.mol

Synonyms:2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate

Chemical Property of 2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate

There total 1 articles about 2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl-4-hydroxy-2-methylthiazole-5-carboxylate (20737-48-8) → sodium ethanolate (141-52-6) + 2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate (92502-98-2)

Guidance literature:

With sodium; In ethanol;

Reference yield:

2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate (92502-98-2) + 3-Trifluoromethylbenzyl chloride (705-29-3) → 2-methyl-5-ethoxy-carbonyl-4-(3-trifluoromethylbenzyloxy)-thiazole

Guidance literature:

In 1-methyl-pyrrolidin-2-one;

Reference yield:

4-fluoro-1-nitro-2-trifluoromethyl-benzene (393-09-9) + 2-methyl-4-oxo-4,5-dihydro-thiazole-5-carboxylic acid ethyl ester; sodium enolate (92502-98-2) → 2-methyl-5-ethoxycarbonyl-4-(4-nitro-3-trifluoromethyl-phenyloxy)-thiazole

Guidance literature:

In 1-methyl-pyrrolidin-2-one; ice-water; ethanol; toluene;

upstream raw materials:

ethyl-4-hydroxy-2-methylthiazole-5-carboxylate